Jean Grisouard
Overview
Explore the profile of Jean Grisouard including associated specialties, affiliations and a list of published articles.
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19
Citations
471
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Recent Articles
11.
Grisouard J, Timper K, Bouillet E, Radimerski T, Dembinski K, Frey D, et al.
Arch Physiol Biochem
. 2011 Feb;
117(4):209-14.
PMID: 21338323
Objective: To study the effects of metformin on lipolysis and hormone sensitive lipase (HSL) phosphorylation in human adipocytes treated with lipolytic and inflammatory agents. Methods: Lipolysis and phosphorylation status of...
12.
Timper K, Grisouard J, Radimerski T, Dembinski K, Peterli R, Haring A, et al.
J Clin Endocrinol Metab
. 2010 Nov;
96(2):E297-303.
PMID: 21106708
Context: Increased plasma levels of glucose-dependent insulinotropic polypeptide (GIP), calcitonin CT gene-related peptide (CGRP)-I, and procalcitonin (Pro-CT) are associated with obesity. Adipocytes express functional GIP receptors and the CT peptides...
13.
Grisouard J, Bouillet E, Timper K, Radimerski T, Dembinski K, Frey D, et al.
Innate Immun
. 2010 Nov;
18(1):25-34.
PMID: 21088047
High fat diet-induced endotoxaemia triggers low-grade inflammation and lipid release from adipose tissue. This study aims to unravel the cellular mechanisms leading to the lipopolysaccharide (LPS) effects in human adipocytes....
14.
Grisouard J, Timper K, Radimerski T, Frey D, Peterli R, Kola B, et al.
Biochem Pharmacol
. 2010 Sep;
80(11):1736-45.
PMID: 20816671
The mechanisms of metformin effects on glucose transport and metabolism were investigated in human adipocytes. Human preadipocytes obtained from surgical biopsies were differentiated in vitro into adipocytes and the effects...
15.
Radimerski T, Grisouard J, Timper K, Zulewski H, Christ-Crain M, Keller U, et al.
Innate Immun
. 2010 Aug;
17(4):403-13.
PMID: 20682585
Severe systemic infections induce ubiquitous calcitonin (CALC) gene expression with release of calcitonin peptides, namely procalcitonin, calcitonin gene-related peptide and adrenomedullin. Using an in vitro model for bacterial infection, we...
16.
Grisouard J, Mayer D
J Steroid Biochem Mol Biol
. 2009 Aug;
117(4-5):87-92.
PMID: 19703560
Protein kinases represent key nodes for the integration of multiple intracellular signalling pathways, resulting in modulation of both ligand-dependent and ligand-independent mechanisms of sex steroid receptor (sSR) signalling cascades. The...
17.
Shukla A, Grisouard J, Ehemann V, Hermani A, Enzmann H, Mayer D
Endocr Relat Cancer
. 2009 Jan;
16(2):429-41.
PMID: 19153208
Insulin and insulin analogs stimulate proliferation of human mammary epithelial cells. We identified and analyzed the signaling pathways related to cell proliferation induced by regular insulin and by four insulin...
18.
Grisouard J, Medunjanin S, Hermani A, Shukla A, Mayer D
Mol Endocrinol
. 2007 Jul;
21(10):2427-39.
PMID: 17609434
Glycogen synthase kinase-3 (GSK-3) plays a key role in the regulation of transcription factors including steroid receptors. Having identified estrogen receptor-alpha (ERalpha) as substrate for GSK-3, the impact of GSK-3...
19.
Medunjanin S, Hermani A, De Servi B, Grisouard J, Rincke G, Mayer D
J Biol Chem
. 2005 Aug;
280(38):33006-14.
PMID: 16076840
Like other steroid hormone receptors, estrogen receptor-alpha (ERalpha) is a substrate for protein kinases, and phosphorylation has profound effects on the function and activity of this receptor. A number of...