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Jean Gautier

Explore the profile of Jean Gautier including associated specialties, affiliations and a list of published articles. Areas
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Articles 75
Citations 4273
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Recent Articles
1.
Liebau R, Waters C, Ahmed A, Soni R, Gautier J
DNA Repair (Amst) . 2024 Oct; 143:103771. PMID: 39383571
DNA interstrand crosslinks (ICLs) are covalent bonds between bases on opposing strands of the DNA helix which prevent DNA melting and subsequent DNA replication or RNA transcription. Here, we show...
2.
Ahmed A, Kato N, Gautier J
J Mol Biol . 2024 May; 436(13):168618. PMID: 38763228
Interstrand crosslinks (ICLs) are a type of covalent lesion that can prevent transcription and replication by inhibiting DNA strand separation and instead trigger cell death. ICL inducing compounds are commonly...
3.
Min J, Gautier J
Cell Res . 2023 Dec; 34(5):337-338. PMID: 38097773
No abstract available.
4.
Min J, Zhao J, Zagelbaum J, Lee J, Takahashi S, Cummings P, et al.
Mol Cell . 2023 Jul; 83(14):2434-2448.e7. PMID: 37402370
Insertions and deletions (indels) are common sources of structural variation, and insertions originating from spontaneous DNA lesions are frequent in cancer. We developed a highly sensitive assay called insertion and...
5.
Dominguez-Sola D, Ying C, Grandori C, Ruggiero L, Chen B, Li M, et al.
Nature . 2023 Jun; 619(7969):E39. PMID: 37386298
No abstract available.
6.
Liebau R, Waters C, Ahmed A, Soni R, Gautier J
bioRxiv . 2023 May; PMID: 37214867
DNA interstrand crosslinks (ICLs) are covalent bonds between bases on opposing strands of the DNA helix which prevent DNA melting and subsequent DNA replication or RNA transcription. Here, we show...
7.
Zagelbaum J, Schooley A, Zhao J, Schrank B, Callen E, Zha S, et al.
Nat Struct Mol Biol . 2023 Apr; 30(7):1048. PMID: 37059902
No abstract available.
8.
Sato M, Liebau R, Liu Z, Liu L, Rabadan R, Gautier J
J Cell Biol . 2023 Feb; 222(3). PMID: 36821090
No abstract available.
9.
Zagelbaum J, Schooley A, Zhao J, Schrank B, Callen E, Zha S, et al.
Nat Struct Mol Biol . 2022 Dec; 30(1):99-106. PMID: 36564591
Nuclear actin-based movements have been shown to orchestrate clustering of DNA double-strand breaks (DSBs) into homology-directed repair domains. Here we describe multiscale three-dimensional genome reorganization following DNA damage and analyze...
10.
Zagelbaum J, Gautier J
DNA Repair (Amst) . 2022 Nov; 121:103430. PMID: 36436496
DNA double-strand breaks (DSBs) are lesions that arise frequently from exposure to damaging agents as well as from ongoing physiological DNA transactions. Mis-repair of DSBs leads to rearrangements and structural...