Jean Boyer
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Explore the profile of Jean Boyer including associated specialties, affiliations and a list of published articles.
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63
Citations
2569
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Recent Articles
1.
Andrade V, Cashman K, Rosenke K, Wilkinson E, Josleyn N, Lynn G, et al.
Commun Med (Lond)
. 2024 Nov;
4(1):253.
PMID: 39609515
Background: We have previously developed a DNA-based vaccine, INO-4500, encoding the Lassa lineage IV glycoprotein precursor. INO-4500, when delivered with electroporation, elicited humoral and cellular responses, and conferred 100% protection...
2.
Jacobson J, Zahrieh D, Strand C, Cruz-Correa M, Pungpapong S, Roberts L, et al.
Cancer Prev Res (Phila)
. 2022 Dec;
16(3):163-173.
PMID: 36534786
Prevention Relevance: The administration of IL12 DNA along with a hepatitis C viral antigen DNA vaccine enhanced the HCV-specific immune responses induced by the vaccine in individuals with chronic hepatitis...
3.
Aggarwal C, Saba N, Algazi A, Sukari A, Seiwert T, Haigentz M, et al.
Clin Cancer Res
. 2022 Dec;
29(3):560-570.
PMID: 36455147
Purpose: Tumoral programmed cell death ligand-1 (PD-L1) expression is common in human papillomavirus (HPV)-associated head and neck squamous cell carcinoma (HNSCC). We assessed whether a DNA vaccine targeting HPV-16/18 E6/E7...
4.
Tebas P, Roberts C, Muthumani K, Reuschel E, Kudchodkar S, Zaidi F, et al.
N Engl J Med
. 2021 Sep;
385(12):e35.
PMID: 34525286
Background: Although Zika virus (ZIKV) infection is typically self-limiting, other associated complications such as congenital birth defects and the Guillain-Barré syndrome are well described. There are no approved vaccines against...
5.
Bhuyan P, Dallas M, Kraynyak K, Herring T, Morrow M, Boyer J, et al.
Hum Vaccin Immunother
. 2020 Nov;
17(5):1288-1293.
PMID: 33175656
VGX-3100 is an investigational DNA-based immunotherapy being developed as an alternative to surgery and ablation for cervical High-Grade Squamous Intraepithelial Lesion (HSIL) with the aim of preserving reproductive health while...
6.
Bhaumik S, Boyer J, Banerjee C, Clark S, Sebastiao N, Vela E, et al.
J Cell Biochem
. 2020 Jul;
121(12):4974-4990.
PMID: 32692912
In preclinical cancer studies, three-dimensional (3D) cell spheroids and aggregates are preferred over monolayer cell cultures due to their architectural and functional similarity to solid tumors. We performed a proof-of-concept...
7.
Smith T, Patel A, Ramos S, Elwood D, Zhu X, Yan J, et al.
Nat Commun
. 2020 May;
11(1):2601.
PMID: 32433465
The coronavirus family member, SARS-CoV-2 has been identified as the causal agent for the pandemic viral pneumonia disease, COVID-19. At this time, no vaccine is available to control further dissemination...
8.
Hasan Y, Furtado L, Tergas A, Lee N, Brooks R, McCall A, et al.
Int J Radiat Oncol Biol Phys
. 2020 Mar;
107(3):487-498.
PMID: 32151670
Purpose: This study assessed the safety and tolerability of therapeutic immunization against the human papillomavirus (HPV) viral oncoproteins E6 and E7 in patients with cervical cancer after chemoradiation. Methods And...
9.
Aggarwal C, Cohen R, Morrow M, Kraynyak K, Sylvester A, Cheung J, et al.
Vaccines (Basel)
. 2020 Feb;
8(1).
PMID: 32013270
Methods: Testing of INO-3016 in animal models confirmed immunogenicity of the DNA-based therapy. A single-site open-label Phase 1 study was initiated for patients with HPV6-positive RRP. Patients were dosed with...
10.
Hollenberg R, Krieger D, Samuels R, Kraynyak K, Sylvester A, Morrow M, et al.
Hum Vaccin Immunother
. 2019 Dec;
16(6):1404-1412.
PMID: 31860383
HPV remains the most common sexually transmitted disease worldwide, despite improvements in awareness, screening, prophylactic vaccination uptake, and surgical treatment. VGX-3100 is an immunotherapy that uses electroporation to introduce DNA...