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» Authors » Jean-Vianney Haure-Mirande

Jean-Vianney Haure-Mirande

Explore the profile of Jean-Vianney Haure-Mirande including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 850
Followers 0
Related Specialties
Neurology
Psychiatry
Molecular Biology
Top 10 Co-Authors
Michelle E Ehrlich
Sam Gandy
Minghui Wang
Bin Zhang
Joel T Dudley
Mickael Audrain
Eric E Schadt
Tomas Fanutza
Ben Readhead
Robert D Blitzer
Published In
Alzheimers Dement
Mol Psychiatry
Acta Neuropathol
Neuron
Oncotarget
Affiliations
Soon will be listed here.
Recent Articles
11.
Clarifying the Potential Role of Microbes in Alzheimer's Disease
Readhead B, Haure-Mirande J, Ehrlich M, Gandy S, Dudley J
Neuron . 2019 Dec; 104(6):1036-1037. PMID: 31855627
No abstract available.
12.
Correction: Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden
Haure-Mirande J, Wang M, Audrain M, Fanutza T, Kim S, Heja S, et al.
Mol Psychiatry . 2018 Nov; 24(3):472. PMID: 30464330
This article was originally published under standard licence, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the paper have been...
13.
Intestinal epithelial Notch-1 protects from colorectal mucinous adenocarcinoma
Dunkin D, Iuga A, Mimouna S, Harris C, Haure-Mirande J, Bozec D, et al.
Oncotarget . 2018 Oct; 9(71):33536-33548. PMID: 30323897
Increasing evidence links Notch-1 signaling with the maintenance of intestinal architecture and homeostasis. Dysfunction in the common Notch-1 pathway transcription factor recombinant binding protein suppressor of hairless (RBP-J) is associated...
14.
Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden
Haure-Mirande J, Wang M, Audrain M, Fanutza T, Kim S, Heja S, et al.
Mol Psychiatry . 2018 Oct; 24(3):431-446. PMID: 30283032
Integrative gene network approaches enable new avenues of exploration that implicate causal genes in sporadic late-onset Alzheimer's disease (LOAD) pathogenesis, thereby offering novel insights for drug-discovery programs. We previously constructed...
15.
Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau
Audrain M, Haure-Mirande J, Wang M, Kim S, Fanutza T, Chakrabarty P, et al.
Mol Psychiatry . 2018 Oct; 24(9):1383-1397. PMID: 30283031
TYROBP/DAP12 forms complexes with ectodomains of immune receptors (TREM2, SIRPβ1, CR3) associated with Alzheimer's disease (AD) and is a network hub and driver in the complement subnetwork identified by multi-scale...
16.
Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus
Readhead B, Haure-Mirande J, Funk C, Richards M, Shannon P, Haroutunian V, et al.
Neuron . 2018 Jun; 99(1):64-82.e7. PMID: 29937276
Investigators have long suspected that pathogenic microbes might contribute to the onset and progression of Alzheimer's disease (AD) although definitive evidence has not been presented. Whether such findings represent a...
17.
Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology
Haure-Mirande J, Audrain M, Fanutza T, Kim S, Klein W, Glabe C, et al.
Acta Neuropathol . 2017 Jun; 134(5):769-788. PMID: 28612290
Conventional genetic approaches and computational strategies have converged on immune-inflammatory pathways as key events in the pathogenesis of late onset sporadic Alzheimer's disease (LOAD). Mutations and/or differential expression of microglial...