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Jean-Philippe Bouchara

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Articles 151
Citations 2552
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Recent Articles
1.
Bidon B, Yaakoub H, Lanoue A, Gery A, Seguin V, Magot F, et al.
Genome Biol Evol . 2025 Mar; PMID: 40052422
Like bacteria and plants, fungi produce a remarkable diversity of small molecules with potent activities for human health known as natural products or secondary metabolites. One such example is mycophenolic...
2.
Saiman L, Waters V, LiPuma J, Hoffman L, Alby K, Zhang S, et al.
Clin Microbiol Rev . 2024 Aug; 37(3):e0021521. PMID: 39158301
SUMMARYThis guidance presents recommendations for clinical microbiology laboratories for processing respiratory samples from people with cystic fibrosis (pwCF). Appropriate processing of respiratory samples is crucial to detect bacterial and fungal...
3.
Barrera C, Schwarz C, Delhaes L, Gal S, Ramel S, Gangneux J, et al.
Mycopathologia . 2024 Jul; 189(4):68. PMID: 39023843
Context: Allergic bronchopulmonary mycoses (ABPM) can be due to molds other than Aspergillus fumigatus in patients with cystic fibrosis (pwCF). We aimed to develop immunoassays for the detection of specific...
4.
Elhaj Mahmoud D, Herivaux A, Morio F, Briard B, Vigneau C, Desoubeaux G, et al.
Biomed J . 2024 Apr; 47(3):100719. PMID: 38580051
Transplant patients, including solid-organ transplant (SOT) and hematopoietic stem cell transplant (HSCT) recipients, are exposed to various types of complications, particularly rejection. To prevent these outcomes, transplant recipients commonly receive...
5.
Ravenel K, Guegan H, Gastebois A, Bouchara J, Gangneux J, Giraud S
Mycopathologia . 2024 Feb; 189(2):19. PMID: 38407729
Filamentous fungi frequently colonize the airways of patients with cystic fibrosis and may cause severe diseases, such as the allergic bronchopulmonary aspergillosis. The most common filamentous fungi capable to chronically...
6.
Burgel P, Southern K, Addy C, Battezzati A, Berry C, Bouchara J, et al.
J Cyst Fibros . 2024 Jan; 23(2):187-202. PMID: 38233247
This is the third in a series of four papers updating the European Cystic Fibrosis Society (ECFS) standards for the care of people with CF. This paper focuses on recognising...
7.
Elhaj Mahmoud D, Hanachi M, Yaakoub H, Blanchard S, Pignon P, Souiai O, et al.
Cytokine . 2023 Oct; 172:156384. PMID: 37832161
Fungal infections caused by Scedosporium species are rising among immunocompromised and immunocompetent patients. Within the immunocompetent group, patients with cystic fibrosis (pwCF) are at high risk of developing a chronic...
8.
Staudt K, Dias B, Alves I, Lelievre B, Bouchara J, Araujo B
Pharmaceutics . 2023 Jul; 15(7). PMID: 37513968
Voriconazole is a triazole antifungal used empirically for the treatment of complicated meningitis associated with . Biopsy studies show that the drug exhibits adequate brain penetration although levels of cerebral...
9.
Santos-Fernandez E, Martin-Souto L, Antoran A, Areitio M, Aparicio-Fernandez L, Bouchara J, et al.
FEMS Microbiol Rev . 2023 Jun; 47(3). PMID: 37286896
The most common genetic hereditary disease affecting Caucasians is cystic fibrosis (CF), which is caused by autosomal recessive mutations in the CFTR gene. The most serious consequence is the production...
10.
Parize P, Fleury M, Poupon-Bourdy S, Persat F, Touzet S, Bienvenu A, et al.
Med Mycol . 2023 Jun; 61(6). PMID: 37263788
Scedosporium and Lomentospora species rank second among the filamentous fungi colonizing the airways of cystic fibrosis (CF) patients. These fungi could be responsible for allergic bronchopulmonary mycosis (ABPM) and bronchitis...