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Jean-Luc Davignon

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Articles 32
Citations 735
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Recent Articles
1.
Mascarau R, Woottum M, Fromont L, Gence R, Cantaloube-Ferrieu V, Vahlas Z, et al.
J Cell Biol . 2023 Mar; 222(5). PMID: 36988579
Macrophages are essential for HIV-1 pathogenesis and represent major viral reservoirs. Therefore, it is critical to understand macrophage infection, especially in tissue macrophages, which are widely infected in vivo, but...
2.
Diallo K, Simons N, Sayegh S, Baron M, Degboe Y, Boyer J, et al.
iScience . 2021 Apr; 24(4):102331. PMID: 33889824
In order to ascertain the significance of transmembrane tumor necrosis factor (tmTNF) reverse signaling , we generated a triple transgenic mouse model (3TG, TNFR1-/-, TNFR2-/-, and tmTNFKI/KI) in which all...
3.
Davignon J, Combe B, Cantagrel A
Arthritis Res Ther . 2021 Jan; 23(1):16. PMID: 33413603
Human cytomegalovirus (HCMV) is a β-herpesvirus that causes inflammation and remains for life in a latent state in their host. HCMV has been at the center of many hypotheses regarding...
4.
Briand-Mesange F, Pons V, Allart S, Masquelier J, Chicanne G, Beton N, et al.
J Biol Chem . 2020 Sep; 295(46):15767-15781. PMID: 32917725
Endocannabinoid signaling plays a regulatory role in various (neuro)biological functions. 2-arachidonoylglycerol (2-AG) is the most abundant endocannabinoid, and although its canonical biosynthetic pathway involving phosphoinositide-specific phospholipase C and diacylglycerol lipase...
5.
Abbas A, Vu Manh T, Valente M, Collinet N, Attaf N, Dong C, et al.
Nat Immunol . 2020 Jul; 21(9):983-997. PMID: 32690951
Plasmacytoid dendritic cells (pDCs) are a major source of type I interferon (IFN-I). What other functions pDCs exert in vivo during viral infections is controversial, and more studies are needed...
6.
Rauwel B, Degboe Y, Diallo K, Sayegh S, Baron M, Boyer J, et al.
J Bone Miner Res . 2019 Dec; 35(4):753-765. PMID: 31834954
Increased osteoclastogenesis is a common feature of bone erosion, notably in osteoporosis but also in inflammatory diseases such as rheumatoid arthritis (RA) and osteoarticular infections. Human cytomegalovirus (HCMV) infection has...
7.
Sayegh S, El Atat O, Diallo K, Rauwel B, Degboe Y, Cavaignac E, et al.
Front Immunol . 2019 Sep; 10:1961. PMID: 31475016
[This corrects the article DOI: 10.3389/fimmu.2019.01482.].
8.
Sayegh S, El Atat O, Diallo K, Rauwel B, Degboe Y, Cavaignac E, et al.
Front Immunol . 2019 Jul; 10:1482. PMID: 31316519
Adipose-derived mesenchymal stem cells (ADSC) have been shown to have remarkable immune-modulating effects. However, their efficacy in clinical trials has yet to be fully demonstrated. This could be due to...
9.
Flammier S, Peyruchaud O, Bourguillault F, Duboeuf F, Davignon J, Norman D, et al.
Arthritis Rheumatol . 2019 Jun; 71(11):1801-1811. PMID: 31162832
Objective: The severity of rheumatoid arthritis (RA) correlates directly with bone erosions arising from osteoclast (OC) hyperactivity. Despite the fact that inflammation may be controlled in patients with RA, those...
10.
Degboe Y, Rauwel B, Baron M, Boyer J, Ruyssen-Witrand A, Constantin A, et al.
Front Immunol . 2019 Feb; 10:3. PMID: 30713533
Macrophages contribute to the pathogenesis of rheumatoid arthritis (RA). They can display different states of activation or "polarization," notably the so-called inflammatory "M1" and the various alternative "M2" polarizations, characterized...