Jean-Francois Daudelin
Overview
Explore the profile of Jean-Francois Daudelin including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
457
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0
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Recent Articles
1.
Lombard-Vadnais F, Collin R, Daudelin J, Chabot-Roy G, Labrecque N, Lesage S
J Immunol
. 2022 Jan;
208(4):898-909.
PMID: 35039332
Type 1 diabetes is an autoimmune disease characterized by pancreatic β cell destruction. It is a complex genetic trait driven by >30 genetic loci with parallels between humans and mice....
2.
Boulet S, Odagiu L, Dong M, LeBel M, Daudelin J, Melichar H, et al.
J Immunol
. 2021 Jul;
207(4):1055-1064.
PMID: 34312259
Central tolerance aims to limit the production of T lymphocytes bearing TCR with high affinity for self-peptide presented by MHC molecules. The accumulation of thymocytes with such receptors is limited...
3.
Nobis C, Cuesta M, Daudelin J, Dubeau Laramee G, Boivin D, Labrecque N, et al.
Methods Mol Biol
. 2020 Dec;
2130:29-51.
PMID: 33284434
In recent years, circadian rhythms have been observed in many aspects of the immune system, both for the innate immunity (the first line of defense against pathogens) and the adaptive...
4.
Odagiu L, Boulet S, De Sousa D, Daudelin J, Nicolas S, Labrecque N
Proc Natl Acad Sci U S A
. 2020 Sep;
117(39):24392-24402.
PMID: 32913051
Enhancing long-term persistence while simultaneously potentiating the effector response of CD8 T cells has been a long-standing goal in immunology to produce better vaccines and adoptive cell therapy products. NR4A3...
5.
Wu N, Cernysiov V, Davidson D, Song H, Tang J, Luo S, et al.
Cell Rep
. 2020 Jan;
30(4):1129-1140.e5.
PMID: 31995754
Plasma membrane damage and cell death during processes such as necroptosis and apoptosis result from cues originating intracellularly. However, death caused by pore-forming agents, like bacterial toxins or complement, is...
6.
Cesaro A, Defrene J, Lachhab A, Page N, Tardif M, Al-Shami A, et al.
PLoS One
. 2019 Aug;
14(8):e0221528.
PMID: 31437241
Expressed strongly by myeloid cells, damage-associated molecular pattern (DAMP) proteins S100A8 and S100A9 are found in the serum of patients with infectious and autoimmune diseases. Compared to S100A9, the role...
7.
Boulet S, Daudelin J, Odagiu L, Pelletier A, Yun T, Lesage S, et al.
Proc Natl Acad Sci U S A
. 2019 Jul;
116(30):15150-15159.
PMID: 31285338
In response to microbial stimulation, monocytes can differentiate into macrophages or monocyte-derived dendritic cells (MoDCs) but the molecular requirements guiding these possible fates are poorly understood. In addition, the physiological...
8.
De Sousa D, Duval F, Daudelin J, Boulet S, Labrecque N
PLoS One
. 2019 Apr;
14(4):e0215012.
PMID: 30951556
During CD8+ T cell response, Notch signaling controls short-lived-effector-cell (SLEC) generation, but the exact mechanisms by which it does so remains unclear. The Notch signaling pathway can act as a...
9.
Wilson A, Shao Z, Grenier V, Mawambo G, Daudelin J, Dejda A, et al.
Sci Immunol
. 2018 Mar;
3(21).
PMID: 29549139
Obesity gives rise to metabolic complications by mechanisms that are poorly understood. Although chronic inflammatory signaling in adipose tissue is typically associated with metabolic deficiencies linked to excessive weight gain,...
10.
Mathieu M, Odagiu L, Gaudot L, Daudelin J, Melichar H, Lapointe R, et al.
Eur J Immunol
. 2016 Nov;
47(2):269-279.
PMID: 27873323
Vaccination with antigen-pulsed CD40-activated B (CD40-B) cells can efficiently lead to the in vivo differentiation of naive CD8 T cells into fully functional effectors. In contrast to bone marrow-derived dendritic...