Jean-Charles Boisset
Overview
Explore the profile of Jean-Charles Boisset including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
1378
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0
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Recent Articles
1.
Sen M, Mooijman D, Chialastri A, Boisset J, Popovic M, Heindryckx B, et al.
Nat Commun
. 2021 Feb;
12(1):1286.
PMID: 33627650
DNA methylation (5mC) is central to cellular identity. The global erasure of 5mC from the parental genomes during preimplantation mammalian development is critical to reset the methylome of gametes to...
2.
Baron C, Kester L, Klaus A, Boisset J, Thambyrajah R, Yvernogeau L, et al.
Nat Commun
. 2018 Jun;
9(1):2517.
PMID: 29955049
Haematopoietic stem cells (HSCs) are generated from haemogenic endothelial (HE) cells via the formation of intra-aortic haematopoietic clusters (IAHCs) in vertebrate embryos. The molecular events controlling endothelial specification, endothelial-to-haematopoietic transition...
3.
Boisset J, Vivie J, Grun D, Muraro M, Lyubimova A, van Oudenaarden A
Nat Methods
. 2018 May;
15(7):547-553.
PMID: 29786092
A cell's function is influenced by the environment, or niche, in which it resides. Studies of niches usually require assumptions about the cell types present, which impedes the discovery of...
4.
Rivron N, Frias-Aldeguer J, Vrij E, Boisset J, Korving J, Vivie J, et al.
Nature
. 2018 May;
557(7703):106-111.
PMID: 29720634
The blastocyst (the early mammalian embryo) forms all embryonic and extra-embryonic tissues, including the placenta. It consists of a spherical thin-walled layer, known as the trophectoderm, that surrounds a fluid-filled...
5.
Mooijman D, Dey S, Boisset J, Crosetto N, van Oudenaarden A
Nat Biotechnol
. 2016 Jun;
34(8):852-6.
PMID: 27347753
The epigenetic DNA modification 5-hydroxymethylcytosine (5hmC) has crucial roles in development and gene regulation. Quantifying the abundance of this epigenetic mark at the single-cell level could enable us to understand...
6.
Grun D, Muraro M, Boisset J, Wiebrands K, Lyubimova A, Dharmadhikari G, et al.
Cell Stem Cell
. 2016 Jun;
19(2):266-277.
PMID: 27345837
Adult mitotic tissues like the intestine, skin, and blood undergo constant turnover throughout the life of an organism. Knowing the identity of the stem cell is crucial to understanding tissue...
7.
Boisset J, Clapes T, Klaus A, Papazian N, Onderwater J, Mommaas-Kienhuis M, et al.
Blood
. 2014 Oct;
125(3):465-9.
PMID: 25301706
Clusters of cells attached to the endothelium of the main embryonic arteries were first observed a century ago. Present in most vertebrate species, such clusters, or intraaortic hematopoietic clusters (IAHCs),...
8.
Boisset J, Clapes T, van der Linden R, Dzierzak E, Robin C
Biol Open
. 2013 Jun;
2(5):525-32.
PMID: 23789102
Integrins are transmembrane receptors that play important roles as modulators of cell behaviour through their adhesion properties and the initiation of signaling cascades. The αIIb integrin subunit (CD41) is one...
9.
Drabek K, Gutierrez L, Vermeij M, Clapes T, Patel S, Boisset J, et al.
Cell Rep
. 2012 Oct;
2(4):781-8.
PMID: 23084744
Mammalian CLASPs are microtubule plus-end tracking proteins whose essential function as regulators of microtubule behavior has been studied mainly in cultured cells. We show here that absence of murine CLASP2...
10.
Boisset J, Robin C
Stem Cell Res
. 2011 Nov;
8(1):1-13.
PMID: 22099016
Hematopoietic Stem Cells (HSCs) are responsible for the production and replenishment of all blood cell types during the entire life of an organism. Generated during embryonic development, HSCs transit through...