Jazmin Aguado-Sierra
Overview
Explore the profile of Jazmin Aguado-Sierra including associated specialties, affiliations and a list of published articles.
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22
Citations
455
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Recent Articles
1.
Dominguez-Gomez P, Zingaro A, Baldo-Canut L, Balzotti C, Darpo B, Morton C, et al.
NPJ Digit Med
. 2024 Dec;
7(1):380.
PMID: 39725693
In silico trials for drug safety assessment require many high-fidelity 3D cardiac simulations to predict drug-induced QT interval prolongation, which is often computationally prohibitive. To streamline this process, we developed...
2.
Aguado-Sierra J, Dominguez-Gomez P, Amar A, Butakoff C, Leitner M, Schaper S, et al.
J Pharmacol Toxicol Methods
. 2024 Mar;
126:107498.
PMID: 38432528
Background And Purpose: A recent paradigm shift in proarrhythmic risk assessment suggests that the integration of clinical, non-clinical, and computational evidence can be used to reach a comprehensive understanding of...
3.
Aguado-Sierra J, Brigham R, Baron A, Gomez P, Houzeaux G, Guerra J, et al.
Methods Mol Biol
. 2023 Sep;
2716:307-334.
PMID: 37702946
Following the 3 R's principles of animal research-replacement, reduction, and refinement-a high-performance computational framework was produced to generate a platform to perform human cardiac in-silico clinical trials as means to...
4.
Gonzalez-Martin P, Sacco F, Butakoff C, Doste R, Bederian C, Gutierrez Espinosa de Los Monteros L, et al.
PLoS One
. 2023 Feb;
18(2):e0263639.
PMID: 36780442
The aim of this work was to analyze the influence of sex hormones and anatomical details (trabeculations and false tendons) on the electrophysiology of healthy human hearts. Additionally, sex- and...
5.
Webber M, Falconer D, Alfarih M, Joy G, Chan F, Davie C, et al.
BMC Cardiovasc Disord
. 2022 Apr;
22(1):140.
PMID: 35365075
Background: The life course accumulation of overt and subclinical myocardial dysfunction contributes to older age mortality, frailty, disability and loss of independence. The Medical Research Council National Survey of Health...
6.
Merino-Caviedes S, Gutierrez L, Alfonso-Almazan J, Sanz-Estebanez S, Cordero-Grande L, Quintanilla J, et al.
Sci Rep
. 2021 Sep;
11(1):18722.
PMID: 34580343
Delayed gadolinium-enhanced cardiac magnetic resonance (LGE-CMR) imaging requires novel and time-efficient approaches to characterize the myocardial substrate associated with ventricular arrhythmia in patients with ischemic cardiomyopathy. Using a translational approach...
7.
Prisco A, Aguado-Sierra J, Butakoff C, Vazquez M, Houzeaux G, Eguzkitza B, et al.
J Cardiovasc Transl Res
. 2021 Feb;
15(2):217-226.
PMID: 33624260
Venous-arterial extracorporeal membrane oxygenation (VA-ECMO) treatment for acute cardiogenic shock in patients who also have acute lung injury predisposes development of a serious complication called "north-south syndrome" (NSS) which causes...
8.
Leon D, Lopez-Yunta M, Alfonso-Almazan J, Marina-Breysse M, Quintanilla J, Sanchez-Gonzalez J, et al.
Europace
. 2019 Jan;
21(5):822-832.
PMID: 30649290
Aims: Myocardial infarction (MI) alters cardiac fibre organization with unknown consequences on ventricular arrhythmia. We used diffusion tensor imaging (DTI) of three-dimensional (3D) cardiac fibres and scar reconstructions to identify...
9.
Garcia-Canadilla P, Dejea H, Bonnin A, Balicevic V, Loncaric S, Zhang C, et al.
Circ Cardiovasc Imaging
. 2018 Oct;
11(10):e007753.
PMID: 30354476
Background: In the era of increasingly successful corrective interventions in patients with congenital heart disease (CHD), global and regional myocardial remodeling are emerging as important sources of long-term morbidity/mortality. Changes...
10.
Lopez-Yunta M, Leon D, Alfonso-Almazan J, Marina-Breysse M, Quintanilla J, Sanchez-Gonzalez J, et al.
Europace
. 2018 Sep;
21(1):163-174.
PMID: 30239689
Aims: We aimed to study the differences in biventricular scar characterization using bipolar voltage mapping compared with state-of-the-art in vivo delayed gadolinium-enhanced cardiac magnetic resonance (LGE-CMR) imaging and ex vivo...