Jayne C Boyer
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Explore the profile of Jayne C Boyer including associated specialties, affiliations and a list of published articles.
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9
Citations
185
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Recent Articles
1.
Boyer J, Taylor L, Nylander-French L
Sci Rep
. 2021 Dec;
11(1):23804.
PMID: 34893638
The isocyanate monomer 1,6-hexamethylene diisocyanate (HDI) and one of its trimers, HDI isocyanurate, are airway and skin sensitizers contained in polyurethane paint. The toxic response of cultured skin cells to...
2.
Taylor L, French J, Robbins Z, Boyer J, Nylander-French L
Front Genet
. 2020 Sep;
11:836.
PMID: 32973864
We evaluated the impact of genetic variance on biomarker levels in a population of workers in the automotive repair and refinishing industry who were exposed to respiratory sensitizers 1,6-hexamethylene diisocyanate...
3.
Winters B, Pleil J, Boyer J, Nylander-French L, Ariel Geer Wallace M, Madden M
Appl In Vitro Toxicol
. 2019 May;
4(2):129-138.
PMID: 31037250
Due to the ∼86,000 chemicals registered under the Toxic Substances Control Act and increasing ethical concerns regarding animal testing, it is not economically or technically feasible to screen every registered...
4.
The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts
Saini N, Roberts S, Klimczak L, Chan K, Grimm S, Dai S, et al.
PLoS Genet
. 2016 Oct;
12(10):e1006385.
PMID: 27788131
Accumulation of somatic changes, due to environmental and endogenous lesions, in the human genome is associated with aging and cancer. Understanding the impacts of these processes on mutagenesis is fundamental...
5.
Nylander-French L, Wu M, French J, Boyer J, Smeester L, Sanders A, et al.
Toxicol Lett
. 2014 Dec;
231(2):217-26.
PMID: 25445006
DNA methylation may mediate inter-individual responses to chemical exposure and, thus, modify biomarker levels of exposure and effects. We analyzed inter-individual differences in inhalation and skin exposure to 1,6-hexamethylene diisocyanate...
6.
Boyer J, Hawk J, Stefanovic L, Farber R
Mutat Res
. 2008 Feb;
640(1-2):89-96.
PMID: 18242644
Although microsatellite mutation rates generally increase with increasing length of the repeat tract, interruptions in a microsatellite may stabilize it. We have performed a direct analysis of the effect of...
7.
Hawk J, Stefanovic L, Boyer J, Petes T, Farber R
Proc Natl Acad Sci U S A
. 2005 Jun;
102(24):8639-43.
PMID: 15932942
Evolutionary studies have suggested that mutation rates vary significantly at different positions in the eukaryotic genome. The mechanism that is responsible for this context-dependence of mutation rates is not understood....
8.
Boyer J, Yamada N, Roques C, Hatch S, Riess K, Farber R
Hum Mol Genet
. 2002 Mar;
11(6):707-13.
PMID: 11912186
We have measured the mutation rates of G(17) and A(17) repeat sequences in cultured mammalian cells with and without mismatch repair and have compared these rates to those of a...
9.
Yamada N, Smith G, Castro A, Roques C, Boyer J, Farber R
Mutat Res
. 2002 Feb;
499(2):213-25.
PMID: 11827714
Microsatellites are DNA elements composed of short tandem repeats of 1-5bp. These sequences are particularly prone to frameshift mutation by insertion-deletion loop formation during replication. The mismatch repair system is...