Jay West
Overview
Explore the profile of Jay West including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
13
Citations
210
Followers
0
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Recent Articles
1.
Poonia S, Goel A, Chawla S, Bhattacharya N, Rai P, Lee Y, et al.
Genome Res
. 2022 Nov;
33(1):80-95.
PMID: 36414416
The identification and characterization of circulating tumor cells (CTCs) are important for gaining insights into the biology of metastatic cancers, monitoring disease progression, and medical management of the disease. The...
2.
Luquette L, Miller M, Zhou Z, Bohrson C, Zhao Y, Jin H, et al.
Nat Genet
. 2022 Sep;
54(10):1564-1571.
PMID: 36163278
Accurate somatic mutation detection from single-cell DNA sequencing is challenging due to amplification-related artifacts. To reduce this artifact burden, an improved amplification technique, primary template-directed amplification (PTA), was recently introduced....
3.
Chemmalil L, Wasalathanthri D, Zhang X, Kuang J, Shao C, Barbour R, et al.
Biotechnol Bioeng
. 2021 Jun;
118(9):3593-3603.
PMID: 34185315
The biopharmaceutical industry is transitioning from currently deployed batch-mode bioprocessing to a highly efficient and agile next-generation bioprocessing with the adaptation of continuous bioprocessing, which reduces capital investment and operational...
4.
Malamas M, Pavlopoulos S, Alapafuja S, Farah S, Zvonok A, Mohammad K, et al.
J Med Chem
. 2021 Apr;
64(9):5956-5972.
PMID: 33900772
-Acylethanolamines are signaling lipid molecules implicated in pathophysiological conditions associated with inflammation and pain. -Acylethanolamine acid amidase (NAAA) favorably hydrolyzes lipid palmitoylethanolamide, which plays a key role in the regulation...
5.
Iyer A, Gupta K, Sharma S, Hari K, Lee Y, Ramalingam N, et al.
J Clin Med
. 2021 Jan;
10(2).
PMID: 33478182
In the published manuscript [...].
6.
Chemmalil L, Prabhakar T, Kuang J, West J, Tan Z, Ehamparanathan V, et al.
Biotechnol Bioeng
. 2020 Aug;
117(12):3757-3765.
PMID: 32776503
Process analytical technology (PAT) has been defined by the Food and Drug Administration as a system for designing, analyzing, and controlling manufacturing through timely measurements to ensure final product quality....
7.
Iyer A, Gupta K, Sharma S, Hari K, Lee Y, Ramalingam N, et al.
J Clin Med
. 2020 Apr;
9(4).
PMID: 32331451
We collated publicly available single-cell expression profiles of circulating tumor cells (CTCs) and showed that CTCs across cancers lie on a near-perfect continuum of epithelial to mesenchymal (EMT) transition. Integrative...
8.
Malamas M, Farah S, Lamani M, Pelekoudas D, Perry N, Rajarshi G, et al.
Bioorg Med Chem
. 2019 Nov;
28(1):115195.
PMID: 31761726
N-acylethanolamine acid amidase (NAAA) inhibition represents an exciting novel approach to treat inflammation and pain. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide...
9.
Kouno T, Moody J, Kwon A, Shibayama Y, Kato S, Huang Y, et al.
Nat Commun
. 2019 Jan;
10(1):360.
PMID: 30664627
Single-cell transcriptomic profiling is a powerful tool to explore cellular heterogeneity. However, most of these methods focus on the 3'-end of polyadenylated transcripts and provide only a partial view of...
10.
Du C, Martin R, Huang Y, Borwankar A, Tan Z, West J, et al.
Biotechnol Bioeng
. 2017 Dec;
115(4):900-909.
PMID: 29205285
Process control for manufacturing biologics is critical for ensuring product quality, safety, and lot to lot consistency of therapeutic proteins. In this study, we investigated the root cause of the...