Jay Lakshman
Overview
Explore the profile of Jay Lakshman including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
3
Citations
12
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
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Published In
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Affiliations
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Recent Articles
1.
Manjunatha U, Lakshminarayana S, Jumani R, Chao A, Young J, Gable J, et al.
Nat Microbiol
. 2024 Oct;
9(11):2817-2835.
PMID: 39379634
Diarrhoeal disease caused by Cryptosporidium is a major cause of morbidity and mortality in young and malnourished children from low- and middle-income countries, with no vaccine or effective treatment. Here...
2.
Lapointe G, Skepper C, Holder L, Armstrong D, Bellamacina C, Blais J, et al.
J Med Chem
. 2021 Apr;
64(9):6329-6357.
PMID: 33929852
Herein, we describe the discovery and optimization of a novel series that inhibits bacterial DNA gyrase and topoisomerase IV binding to, and stabilization of, DNA cleavage complexes. Optimization of this...
3.
Jumani R, Blais J, Tillmann H, Segal F, Wetty D, Ostermeier C, et al.
ACS Infect Dis
. 2021 Apr;
7(5):959-968.
PMID: 33822577
Cryptosporidiosis is a leading cause of moderate-to-severe diarrhea in low- and middle-income countries, responsible for high mortality in children younger than two years of age, and it is also strongly...