Jay Chandar
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Explore the profile of Jay Chandar including associated specialties, affiliations and a list of published articles.
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12
Citations
20
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Recent Articles
1.
Seetharam D, Chandar J, Ramsoomair C, Desgraves J, Medina A, Hudson A, et al.
bioRxiv
. 2024 Oct;
PMID: 39464150
Viral mimicry refers to the activation of innate anti-viral immune responses due to the induction of endogenous retroelement (RE) expression. Viral mimicry has been previously described to augment anti-tumor immune...
2.
Rivera C, Bhatia S, Morell A, Daggubati L, Merenzon M, Sheriff S, et al.
J Neurooncol
. 2024 Aug;
170(3):579-589.
PMID: 39180640
Purpose: Recurrence for high-grade gliomas is inevitable despite maximal safe resection and adjuvant chemoradiation, and current imaging techniques fall short in predicting future progression. However, we introduce a novel whole-brain...
3.
Lu V, Gurses M, Shah K, Chandar J, Khalafallah A, Shah A, et al.
World Neurosurg
. 2024 Jul;
189:e898-e903.
PMID: 38986945
Background: The use of robot-assisted laser interstitial thermal therapy (LITT) is emerging as a viable treatment option for brain tumors in patients aged 80-90 years (octogenarians). Correspondingly, the aim of...
4.
Gurses M, Lu V, Gecici N, Gokalp E, Shah K, Metzler A, et al.
J Neurosurg
. 2024 May;
141(5):1281-1291.
PMID: 38820611
Objective: Real-time MRI-guided focused laser interstitial thermal therapy (LITT) is a minimally invasive surgical treatment choice for challenging intracranial lesions that are either resistant to conventional therapies or located in...
5.
Desgraves J, Valdez M, Chandar J, Gurses M, Henderson L, Castro J, et al.
Cancers (Basel)
. 2024 May;
16(10).
PMID: 38792022
Purpose: The limited efficacy of current treatments for malignant brain tumors necessitates novel therapeutic strategies. This study aimed to assess the potential of antisense oligonucleotides (ASOs) as adjuvant therapy for...
6.
Merenzon M, Valdez M, Chandar J, Lu V, Del Pont F, Morell A, et al.
J Neurosurg
. 2024 Apr;
140(4):949-957.
PMID: 38564815
Objective: The authors aimed to review the frontal lobe's surgical anatomy, describe their keyhole frontal lobectomy technique, and analyze the surgical results. Methods: Patients with newly diagnosed frontal gliomas treated...
7.
Metagenome analyses identify human endogenous retrovirus-K113 (HML-2) subtype in glioblastoma. Reply
Govindarajan V, Chandar J, Nath A, Shah A
J Clin Invest
. 2023 Dec;
133(24).
PMID: 38099503
No abstract available.
8.
Daggubati L, Ramos-Fresnedo A, Merenzon M, Bhatia S, Morell A, Berry K, et al.
Oper Neurosurg (Hagerstown)
. 2023 Oct;
25(5):435-440.
PMID: 37846139
Background And Objectives: Bilateral/butterfly glioblastoma (bGBM) has a poor prognosis. Resection of these tumors is limited due to severe comorbidities that arise from surgical procedures. Laser interstitial thermal therapy (LITT)...
9.
Shah A, Rivas S, Doucet-OHare T, Govindarajan V, DeMarino C, Wang T, et al.
J Clin Invest
. 2023 Jul;
133(13).
PMID: 37395282
Human endogenous retroviruses (HERVs) are ancestral viral relics that constitute nearly 8% of the human genome. Although normally silenced, the most recently integrated provirus HERV-K (HML-2) can be reactivated in...
10.
Valdez M, Kim E, Bhatia S, Saad A, Sidani C, Daggubati L, et al.
Microb Pathog
. 2023 Jun;
181:106211.
PMID: 37343897
Introduction: Herpes Simplex Virus-1 (HSV-1) is a neurotropic DNA virus with neural latency and stereotypic viral encephalitis. It has been reported to conceal underlying glioblastoma (GBM) due to similar radiographic...