Jason Spence
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Explore the profile of Jason Spence including associated specialties, affiliations and a list of published articles.
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7
Citations
424
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Recent Articles
1.
Jo K, Liu Z, Patel G, Yu Z, Yao L, Teague S, et al.
bioRxiv
. 2024 Jul;
PMID: 39026750
The role of FGF is the least understood of the morphogens driving mammalian gastrulation. Here we investigated the function of FGF in a stem cell model for human gastrulation known...
2.
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
Gu W, Wang H, Huang X, Kraiczy J, Singh P, Ng C, et al.
Cell Stem Cell
. 2021 Sep;
29(1):101-115.e10.
PMID: 34582804
Adult stem cells maintain regenerative tissue structure and function by producing tissue-specific progeny, but the factors that preserve their tissue identities are not well understood. The small and large intestines...
3.
Vanoni S, Zeng C, Marella S, Uddin J, Wu D, Arora K, et al.
J Allergy Clin Immunol
. 2019 Oct;
145(1):239-254.e2.
PMID: 31647967
Background: The pathology of eosinophilic esophagitis (EoE) is characterized by eosinophil-rich inflammation, basal zone hyperplasia (BZH), and dilated intercellular spaces, and the underlying processes that drive the pathologic manifestations of...
4.
Golob J, DeMeules M, Loeffelholz T, Quinn Z, Dame M, Silvestri S, et al.
Blood Adv
. 2019 Oct;
3(19):2866-2869.
PMID: 31585950
No abstract available.
5.
Quiros M, Nishio H, Neumann P, Siuda D, Brazil J, Azcutia V, et al.
J Clin Invest
. 2017 Aug;
127(9):3510-3520.
PMID: 28783045
In response to injury, epithelial cells migrate and proliferate to cover denuded mucosal surfaces and repair the barrier defect. This process is orchestrated by dynamic crosstalk between immune cells and...
6.
Procyshyn T, Spence J, Read S, Watson N, Crespi B
Biol Lett
. 2017 Apr;
13(4).
PMID: 28424317
The neurohormone oxytocin plays a central role in human social behaviour and cognition, and oxytocin dysregulation may contribute to psychiatric disorders. However, genetic factors influencing individual variation in the oxytocinergic...
7.
Aylor D, Valdar W, Foulds-Mathes W, Buus R, Verdugo R, Baric R, et al.
Genome Res
. 2011 Mar;
21(8):1213-22.
PMID: 21406540
The Collaborative Cross (CC) is a mouse recombinant inbred strain panel that is being developed as a resource for mammalian systems genetics. Here we describe an experiment that uses partially...