Jason Signolet
Overview
Explore the profile of Jason Signolet including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
336
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0
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Recent Articles
1.
Bornelov S, Reynolds N, Xenophontos M, Gharbi S, Johnstone E, Floyd R, et al.
Mol Cell
. 2018 Jul;
71(1):56-72.e4.
PMID: 30008319
Chromatin remodeling complexes play essential roles in metazoan development through widespread control of gene expression, but the precise molecular mechanisms by which they do this in vivo remain ill defined....
2.
OShaughnessy-Kirwan A, Signolet J, Costello I, Gharbi S, Hendrich B
Development
. 2015 Jun;
142(15):2586-97.
PMID: 26116663
Chromatin remodelling proteins are essential for different aspects of metazoan biology, yet functional details of why these proteins are important are lacking. Although it is possible to describe the biochemistry...
3.
Signolet J, Hendrich B
FEBS J
. 2014 Oct;
282(9):1692-702.
PMID: 25354247
Proteins that modify the structure of chromatin are known to be important for various aspects of metazoan biology including development, disease and possibly ageing. Yet functional details of why these...
4.
Reynolds N, Latos P, Hynes-Allen A, Loos R, Leaford D, OShaughnessy A, et al.
Cell Stem Cell
. 2012 May;
10(5):583-94.
PMID: 22560079
Transcriptional heterogeneity within embryonic stem cell (ESC) populations has been suggested as a mechanism by which a seemingly homogeneous cell population can initiate differentiation into an array of different cell...
5.
Towers M, Signolet J, Sherman A, Sang H, Tickle C
Nat Commun
. 2011 Aug;
2:426.
PMID: 21829188
The proposal that birds descended from theropod dinosaurs with digits 2, 3 and 4 was recently given support by short-term fate maps, suggesting that the chick wing polarizing region-a group...
6.
Durand C, Bangs F, Signolet J, Decker E, Tickle C, Rappold G
Eur J Hum Genet
. 2009 Dec;
18(5):527-32.
PMID: 19997128
Léri-Weill Dyschondrosteosis (LWD) is a dominant skeletal disorder characterized by short stature and distinct bone anomalies. SHOX gene mutations and deletions of regulatory elements downstream of SHOX resulting in haploinsufficiency...