Jason P Appleton
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Explore the profile of Jason P Appleton including associated specialties, affiliations and a list of published articles.
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53
Citations
713
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Recent Articles
1.
Appleton J, Dixon M, Woodhouse L, Anderson C, Ankolekar S, Cala L, et al.
Eur J Neurol
. 2024 Oct;
31(12):e16502.
PMID: 39392040
Background And Purpose: Ambulance trials assessing interventions in suspected stroke patients will recruit patients with currently active symptoms that will resolve into transient ischaemic attack (TIA). The safety and efficacy...
2.
Blair G, Appleton J, Mhlanga I, Woodhouse L, Doubal F, Bath P, et al.
Stroke Vasc Neurol
. 2024 Apr;
9(6):581-594.
PMID: 38569894
Cerebral small vessel disease (cSVD) causes lacunar stroke (25% of ischaemic strokes), haemorrhage, dementia, physical frailty, or is 'covert', but has no specific treatment. Uncertainties about the design of clinical...
3.
Marei O, Podlasek A, Soo E, Butt W, Gory B, Nguyen T, et al.
J Neurointerv Surg
. 2024 Jan;
PMID: 38253378
Background: Half of patients who achieve successful recanalization following endovascular thrombectomy (EVT) for acute ischemic stroke experience poor functional outcome. We aim to investigate whether the use of adjunctive intra-arterial...
4.
Bose S, Papathanasiou A, Karkhanis S, Appleton J, King D, Batra R, et al.
J Neurol
. 2023 Aug;
270(12):6193-6206.
PMID: 37608221
Susac syndrome is a likely autoimmune microangiopathy affecting the brain, retina and inner ear. Due to the rarity of this condition, diagnosis and treatment can be challenging. Diagnosis is based...
5.
Woodhouse L, Appleton J, Ankolekar S, England T, Mair G, Muir K, et al.
BMJ Neurol Open
. 2023 Aug;
5(1):e000424.
PMID: 37564156
Background: The Rapid Intervention with Glyceryl Trinitrate in Hypertensive Stroke Trial-2 (RIGHT-2) reported no overall treatment difference between glyceryl trinitrate (GTN) and sham at day 90. Here we assess participants'...
6.
Woodhouse L, Appleton J, Christensen H, Dineen R, England T, James M, et al.
Sci Rep
. 2023 Jul;
13(1):11717.
PMID: 37474599
Intensive antiplatelet therapy did not reduce recurrent stroke/transient ischaemic attack (TIA) events as compared with guideline treatment in the Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke (TARDIS) trial, but...
7.
Dixon M, Appleton J, Siriwardena A, Williams J, Bath P
Neurol Sci
. 2023 Jul;
44(12):4363-4378.
PMID: 37405524
Background: Treatment for stroke is time-dependent, and ambulance services play a vital role in the early recognition, assessment and transportation of stroke patients. Innovations which begin in ambulance services to...
8.
Krishnan K, Law Z, Minhas J, Bath P, Robinson T, Sprigg N, et al.
Clin Med (Lond)
. 2022 Dec;
22(5):449-454.
PMID: 36507812
Acute stroke is the leading cause of disability in the UK and a leading cause of mortality worldwide. The majority of patients with ischaemic stroke present with minor deficits or...
9.
Dixon M, Appleton J, Scutt P, Woodhouse L, Haywood L, Havard D, et al.
BMJ Open
. 2022 Nov;
12(11):e060211.
PMID: 36410799
Objectives: Ambulances offer the first opportunity to evaluate hyperacute stroke treatments. In this study, we investigated the conduct of a hyperacute stroke study in the ambulance-based setting with a particular...
10.
Dhillon P, Butt W, Podlasek A, McConachie N, Lenthall R, Nair S, et al.
Stroke
. 2022 May;
53(9):2770-2778.
PMID: 35506384
Background: The impact on clinical outcomes of patient selection using perfusion imaging for endovascular thrombectomy (EVT) in patients with acute ischemic stroke presenting beyond 6 hours from onset remains undetermined...