Jason N Peart
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Explore the profile of Jason N Peart including associated specialties, affiliations and a list of published articles.
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1372
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Recent Articles
1.
Budiono B, Budiono B, Vider J, Zaid A, Peart J, Du Toit E, et al.
Am J Physiol Regul Integr Comp Physiol
. 2025 Jan;
328(2):R206-R219.
PMID: 39792091
Physical activity improves myocardial structure, function, and resilience via complex, incompletely defined mechanisms. We explored the effects of 1- to 2-wk swim training on cardiac and systemic phenotype in young...
2.
Robertson K, Griffith T, Helman T, Hatton-Jones K, Naghipour S, Robertson D, et al.
J Dev Orig Health Dis
. 2024 Sep;
15:e14.
PMID: 39291337
Early life stress (ELS) and a Western diet (WD) promote mood and cardiovascular disorders, however, how these risks interact in disease pathogenesis is unclear. We assessed effects of ELS with...
3.
Kuck L, McNamee A, Bordukova M, Sadafi A, Marr C, Peart J, et al.
Proc Natl Acad Sci U S A
. 2024 Aug;
121(36):e2407765121.
PMID: 39207733
Hematopoietic stem cells surrender organelles during differentiation, leaving mature red blood cells (RBC) devoid of transcriptional machinery and mitochondria. The resultant absence of cellular repair capacity limits RBC circulatory longevity,...
4.
Naghipour S, Cox A, Fisher J, Plan M, Stark T, West N, et al.
Diabetol Metab Syndr
. 2024 Jun;
16(1):133.
PMID: 38886825
Background: Elevations in the gut metabolite trimethylamine-N-oxide (TMAO) have been linked to cardiovascular and metabolic diseases. Whether elevated TMAO levels reflect early mechanistic involvement or a sequela of evolving disease...
5.
Naghipour S, Fisher J, Perkins A, Peart J, Headrick J, Du Toit E
Dis Model Mech
. 2023 Apr;
16(5).
PMID: 37078591
Trimethylamine-N-oxide (TMAO) is an end-product of gut microbiome metabolism linked to cardiovascular disease (CVD). However, precise cardiovascular influences of the TMAO concentrations reported in early or severe disease remain to...
6.
Griffith T, Russell J, Naghipour S, Helman T, Peart J, Stapelberg N, et al.
Life Sci
. 2022 Nov;
311(Pt A):121137.
PMID: 36349604
Aim: Evolving type 2 diabetes (T2D) may influence locomotion and affective state, promoting metabolic dysfunction. We examined behaviour and neurobiology in a model of T2D, testing for benefits with dietary...
7.
Helman T, Headrick J, Vider J, Peart J, Stapelberg N
J Neurosci Res
. 2022 Sep;
100(11):2004-2027.
PMID: 36059192
Psychosocial stress promotes and links mood and cardiovascular disorders in a sex-specific manner. However, findings in animal models are equivocal, in some cases opposing human dimorphisms. We examined central nervous...
8.
Helman T, Headrick J, Peart J, Stapelberg N
Eur J Neurosci
. 2022 Jun;
56(4):4333-4362.
PMID: 35763309
Stress resilience, and behavioural and cardiovascular impacts of chronic stress, are theorised to involve integrated neuro-endocrine/inflammatory/transmitter/trophin signalling. We tested for this integration, and whether behaviour/emotionality, together with myocardial ischaemic tolerance,...
9.
Kuck L, Peart J, Simmonds M
Am J Physiol Heart Circ Physiol
. 2022 May;
323(1):H24-H37.
PMID: 35559724
Mature circulating red blood cells (RBCs) are classically viewed as passive participants in circulatory function, given erythroblasts eject their organelles during maturation. Endogenous production of nitric oxide (NO) and its...
10.
Hatton-Jones K, Cox A, Peart J, Headrick J, Du Toit E
Physiol Rep
. 2022 Jan;
10(2):e15170.
PMID: 35076176
Although both diet-induced obesity and psychological stress are recognized as significant independent contributors to cardiometabolic and behavioral disorders, our understanding of how these two disorders interact and influence cardiometabolic risk...