Jason E Sanchez
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Explore the profile of Jason E Sanchez including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
25
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Recent Articles
1.
Sanchez J, Guo W, Li C, Li L, Xiao C
bioRxiv
. 2025 Feb;
PMID: 39974893
The jelly roll (JR) fold is the most common structural motif found in the capsid and nucleocapsid of viruses. Its pervasiveness across many different viral families motives developing a tool...
2.
Guo W, Alarcon E, Sanchez J, Xiao C, Li L
bioRxiv
. 2025 Feb;
PMID: 39896532
PBCV-1, a giant virus classified among the Nucleocytoviricota virus (NCV) whose structure has been determined to near atomic resolution. The majority capsomers forming the capsid of PBCV 1 are Type...
3.
Guo W, Alarcon E, Sanchez J, Xiao C, Li L
Cells
. 2025 Jan;
13(24.
PMID: 39768179
Viral capsid assembly is a complex and critical process, essential for understanding viral behavior, evolution, and the development of antiviral treatments, vaccines, and nanotechnology. Significant progress in studying viral capsid...
4.
Guo W, Gao Y, Du D, Sanchez J, Visootsat A, Li Y, et al.
bioRxiv
. 2024 Jun;
PMID: 38853942
BimC family proteins are bipolar motor proteins belonging to the kinesin superfamily which promote mitosis by crosslinking and sliding apart antiparallel microtubules. Understanding the binding mechanism between the kinesin and...
5.
Sun S, Rodriguez G, Zhao G, Sanchez J, Guo W, Du D, et al.
Brief Bioinform
. 2024 Mar;
25(2).
PMID: 38446738
The family of Janus Kinases (JAKs) associated with the JAK-signal transducers and activators of transcription signaling pathway plays a vital role in the regulation of various cellular processes. The conformational...
6.
Bound ion effects: Using machine learning method to study the kinesin Ncd's binding with microtubule
Guo W, Du D, Zhang H, Sanchez J, Sun S, Xu W, et al.
Biophys J
. 2023 Dec;
123(17):2740-2748.
PMID: 38160255
Drosophila Ncd proteins are motor proteins that play important roles in spindle organization. Ncd and the tubulin dimer are highly charged. Thus, it is crucial to investigate Ncd-tubulin dimer interactions...
7.
Sun S, Rodriguez G, Xie Y, Guo W, Hernandez A, Sanchez J, et al.
Life (Basel)
. 2023 Apr;
13(4).
PMID: 37109511
Janus Kinase 3 (JAK3) plays a key role in the development, proliferation, and differentiation of various immune cells. It regulates gene expression by phosphorylation of Signal Transducers and Activators of...
8.
Sun S, Xu H, Xie Y, Sanchez J, Guo W, Liu D, et al.
Comput Struct Biotechnol J
. 2023 Feb;
21:1383-1389.
PMID: 36817955
Electrostatic features are fundamental to protein functions and protein-protein interactions. Studying highly charged biomolecules is challenging given the heterogeneous distribution of the ionic cloud around such biomolecules. Here we report...
9.
Guo W, Ale T, Sun S, Sanchez J, Li L
Cells
. 2023 Jan;
12(2).
PMID: 36672172
Microtubules are key players in several stages of the cell cycle and are also involved in the transportation of cellular organelles. Microtubules are polymerized by α/β tubulin dimers with a...
10.
Guo W, Sun S, Sanchez J, Lopez-Hernandez A, Ale T, Chen J, et al.
Comput Struct Biotechnol J
. 2022 Sep;
20:4305-4314.
PMID: 36051882
Kinesins are microtubule-based motor proteins that play important roles ranging from intracellular transport to cell division. Human Kinesin-5 (Eg5) is essential for mitotic spindle assembly during cell division. By combining...