Jason E Norton
Overview
Explore the profile of Jason E Norton including associated specialties, affiliations and a list of published articles.
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9
Citations
471
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Recent Articles
1.
Harris D, Pollock S, Wood E, Goiffon R, Klingele A, Cabot E, et al.
J Bacteriol
. 2009 Jun;
191(16):5240-52.
PMID: 19502398
We have generated extreme ionizing radiation resistance in a relatively sensitive bacterial species, Escherichia coli, by directed evolution. Four populations of Escherichia coli K-12 were derived independently from strain MG1655,...
2.
Matejkova P, Strouhal M, Smajs D, Norris S, Palzkill T, Petrosino J, et al.
BMC Microbiol
. 2008 May;
8:76.
PMID: 18482458
Background: Syphilis spirochete Treponema pallidum ssp. pallidum remains the enigmatic pathogen, since no virulence factors have been identified and the pathogenesis of the disease is poorly understood. Increasing rates of...
3.
Williams S, Tait-Kamradt A, Norton J, Albert T, Dougherty T
J Microbiol Methods
. 2007 May;
70(1):65-74.
PMID: 17477996
The Gram-positive pathogen Streptococcus pneumoniae, which can be responsible for serious cases of pneumonia and meningitis, has been intensely studied for almost 100 years. Many of the key experiments have...
4.
Hersh B, Nelson C, Stoll S, Norton J, Albert T, Carroll S
Dev Biol
. 2006 Dec;
302(2):717-27.
PMID: 17174297
Hox proteins have been proposed to act at multiple levels within regulatory hierarchies and to directly control the expression of a plethora of target genes. However, for any specific Hox...
5.
Manjunatha U, Boshoff H, Dowd C, Zhang L, Albert T, Norton J, et al.
Proc Natl Acad Sci U S A
. 2006 Jan;
103(2):431-6.
PMID: 16387854
PA-824 is a promising new compound for the treatment of tuberculosis that is currently undergoing human trials. Like its progenitors metronidazole and CGI-17341, PA-824 is a prodrug of the nitroimidazole...
6.
Albert T, Dailidiene D, Dailide G, Norton J, Kalia A, Richmond T, et al.
Nat Methods
. 2005 Nov;
2(12):951-3.
PMID: 16299480
We developed a microarray hybridization-based method, 'comparative genome sequencing' (CGS), to find mutations in bacterial genomes and used it to study metronidazole resistance in H. pylori. CGS identified mutations in...
7.
Wong C, Albert T, Vega V, Norton J, Cutler D, Richmond T, et al.
Genome Res
. 2004 Mar;
14(3):398-405.
PMID: 14993206
Mutations in the SARS-Coronavirus (SARS-CoV) can alter its clinical presentation, and the study of its mutation patterns in human populations can facilitate contact tracing. Here, we describe the development and...
8.
Johnson K, Norton J, Bresnick E
Nucleic Acids Res
. 2002 Mar;
30(7):1522-30.
PMID: 11917012
Strong transactivation of the beta-globin genes is conferred by the beta-globin locus control region (LCR), which consists of four erythroid-specific DNase I hypersensitive sites (HS1-HS4). HS2 has a powerful enhancer...
9.
Chu J, Jeffries S, Norton J, Capobianco A, Bresnick E
J Biol Chem
. 2001 Dec;
277(9):7587-97.
PMID: 11739397
Developmental decisions that control cell fate are commonly regulated by the Notch signaling pathway. Activation of transmembrane Notch receptors results in proteolytic liberation of the intracellular domain of Notch, which...