Jason D Huber
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Explore the profile of Jason D Huber including associated specialties, affiliations and a list of published articles.
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65
Citations
1747
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Recent Articles
1.
Ghahremani P, BaniArdalan S, Alehossein P, Parveen A, Jorjani M, Brown C, et al.
Life Sci
. 2024 Dec;
361:123336.
PMID: 39719167
Aims: Post stroke hyperglycemia has been shown to deter functional recovery. Earlier findings have indicated the cap-dependent translation regulator 4E-BP1 is detrimentally upregulated in hyperglycemic conditions. The present study aims...
2.
Geldenhuys W, Wilson G, Hernandez K, Monaghan K, Smith K, Cicala D, et al.
J Alzheimers Dis
. 2024 Dec;
103(2):429-440.
PMID: 39639511
Background: Mitochondrial dysfunction is implicated in several neurodegenerative diseases associated with memory and cognitive deficits, including Alzheimer's disease. Changes in bioenergetic function results in reactive oxygen species, oxidative damage and...
3.
Barbosa Belchior M, Kane R, Huber J, Geldenhuys W
Bioorg Med Chem Lett
. 2024 Dec;
117():130045.
PMID: 39631473
Monoamine oxidase (MAO) B is a promising target for treating stroke reperfusion injury, Parkinson's disease as well as other neurodegenerative diseases. Pharmacological inhibitors of this enzyme have demonstrated the ability...
4.
Newton E, Starcovic S, Menze M, Konkle M, Long T, Hazlehurst L, et al.
Bioorg Med Chem Lett
. 2023 May;
89:129310.
PMID: 37137430
MitoNEET belongs to the CDGSH Iron-Sulfur Domain (CISD)-gene family of proteins and is a [2Fe-2S] cluster-containing protein found on the outer membrane of mitochondria. The specific functions of mitoNEET/CISD1 remain...
5.
Vijikumar A, Saralkar P, Saylor S, Sullivan P, Huber J, Geldenhuys W
Exp Neurol
. 2022 Jun;
355:114128.
PMID: 35662609
Cerebral ischemic stroke is a leading cause of mortality and disability worldwide. Currently, there are a lack of drugs capable of reducing neuronal cell loss due to ischemia/reperfusion-injury after stroke....
6.
Hernandez A, Tan C, Plattner F, Logsdon A, Pozo K, Yousuf M, et al.
Mol Brain
. 2021 Nov;
14(1):164.
PMID: 34758856
No abstract available.
7.
Saralkar P, Mdzinarishvili A, Arsiwala T, Lee Y, Sullivan P, Pinti M, et al.
Pharm Res
. 2021 May;
38(5):803-817.
PMID: 33982226
Purpose: Therapeutic strategies to treat ischemic stroke are limited due to the heterogeneity of cerebral ischemic injury and the mechanisms that contribute to the cell death. Since oxidative stress is...
8.
Logsdon A, Lucke-Wold B, Turner R, Collins S, Reeder E, Huber J, et al.
J Vis Exp
. 2020 Nov;
(165).
PMID: 33226021
Traumatic brain injury (TBI) is a large-scale public health problem. Mild TBI is the most prevalent form of neurotrauma and accounts for a large number of medical visits in the...
9.
Hernandez A, Tan C, Plattner F, Logsdon A, Pozo K, Yousuf M, et al.
Mol Brain
. 2018 Nov;
11(1):64.
PMID: 30409147
Direct or indirect exposure to an explosion can induce traumatic brain injury (TBI) of various severity levels. Primary TBI from blast exposure is commonly characterized by internal injuries, such as...
10.
Gao F, Lucke-Wold B, Li X, Logsdon A, Xu L, Xu S, et al.
Front Physiol
. 2018 Jan;
8:1124.
PMID: 29367846
Nitric oxide (NO) is a known anti-adhesive molecule that prevents platelet aggregation and leukocyte adhesion to endothelial cells (ECs). The mechanism has been attributed to its role in the regulation...