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Jason Clement

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Articles 17
Citations 101
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Recent Articles
1.
Hwang N, Ban H, Wu S, McGuire K, Hernandez E, Chen J, et al.
Bioorg Med Chem Lett . 2022 Jan; 58:128518. PMID: 34979256
Hepatitis B virus (HBV) core protein, the building block of the HBV capsid, plays multiple roles in viral replication, and is an attractive target for development of antiviral agents with...
2.
Berland T, Clement J, Inston N, Kreienberg P, Ouriel K
J Vasc Surg . 2021 Oct; 75(3):1038-1046.e3. PMID: 34601046
Background: Percutaneous devices for creation of native arteriovenous fistulae offer an alternative to traditional open surgical techniques. The 4F WavelinQ EndoAVF System was developed as a lower profile alternative to...
3.
Mordhorst A, Clement J, Kiaii M, Faulds J, Hsiang Y, Misskey J
J Vasc Surg . 2021 Jul; 75(1):238-247.e1. PMID: 34303803
Objective: Preliminary outcomes for percutaneous endovascular autogenous access (endoAVF) have shown promising results; however, comparisons with surgical cohorts in dialysis populations are lacking. This study compares autogenous arteriovenous access created...
4.
Hwang N, Pei Y, Clement J, Robertson E, Du Y
Bioorg Med Chem Lett . 2020 Sep; 30(23):127553. PMID: 32971261
Brusatol, a quassinoid natural product, is effective against multiple diseases including hematologic malignancies, as we reported recently by targeting the PI3Kγ isoform, but toxicity limits its further development. Herein, we...
5.
Du Y, Valenciano A, Dai Y, Zheng Y, Zhang F, Zhang Y, et al.
J Nat Prod . 2019 Oct; 83(3):569-577. PMID: 31577436
In our continuing search for novel natural products with antiplasmodial activity, an extract of was found to have good activity, with an IC value less than 1.25 μg/mL. After bioassay-directed...
6.
Berland T, Clement J, Griffin J, Westin G, Ebner A
Ann Vasc Surg . 2019 May; 60:182-192. PMID: 31075457
Background: The use of arteriovenous fistula (AVF) is hampered by long surgical wait times, slow maturation, and upwards of 60% that do not mature. We describe our clinical experience in...
7.
Cho N, Valenciano A, Du Y, Clement J, Cassera M, Goetz M, et al.
Bioorg Med Chem Lett . 2018 Sep; 28(20):3368-3371. PMID: 30219526
Bioassay-guided fractionation of an extract of Carpha glomerata (Cyperaceae) led to the isolation of seven compounds. Compounds 1 (carphorin A), 3 (carphorin C), 4 (carphorin D), and 5 (carphabene) are...
8.
Cho N, Du Y, Valenciano A, Fernandez-Murga M, Goetz M, Clement J, et al.
Bioorg Med Chem Lett . 2017 Nov; 28(1):40-42. PMID: 29162457
A bioassay-guided fractionation and chemical investigation of Amaryllis belladonna Steud. bulbs resulted in the isolation and identification of the new crinane alkaloid 1,4-dihydroxy-3-methoxy powellan (1), along with the 3 known...
9.
Lok C, Rajan D, Clement J, Kiaii M, Sidhu R, Thomson K, et al.
Am J Kidney Dis . 2017 Jun; 70(4):486-497. PMID: 28624422
Background: Hemodialysis arteriovenous fistulas (AVFs) are suboptimally used primarily due to problems with maturation, early thrombosis, and patient nonacceptance. An endovascular approach to fistula creation without open surgery offers another...
10.
Romann A, Beaulieu M, Rheaume P, Clement J, Sidhu R, Kiaii M
J Vasc Access . 2015 Dec; 17(2):167-74. PMID: 26660034
Purpose: Improving arteriovenous fistula (AVF) patency is an integral part of the care of hemodialysis patients, often requiring procedures such as percutaneous transluminal angioplasty (PTA). However, these interventions may fail...