Jason B Shear
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Explore the profile of Jason B Shear including associated specialties, affiliations and a list of published articles.
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Articles
49
Citations
931
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Recent Articles
1.
Hernandez D, Michelson K, Romanovicz D, Ritschdorff E, Shear J
Bioprinting
. 2023 Aug;
28.
PMID: 37601117
Independent control over the Young's modulus and topography of a hydrogel cell culture substrate is necessary to characterize how attributes of its adherent surface affect cellular responses. Arbitrary, real-time manipulation...
2.
2-Amino-3'-dialkylaminobiphenyl-based fluorescent intracellular probes for nitric oxide surrogate NO
Escamilla P, Shen Y, Zhang Q, Hernandez D, Howard C, Qian X, et al.
Chem Sci
. 2021 Jun;
11(5):1394-1403.
PMID: 34123264
Fluorescent probes for nitric oxide (NO), or more frequently for its oxidized surrogate dinitrogen trioxide (NO), have enabled scientists to study the contributions of this signaling molecule to many physiological...
3.
Hardy J, Hernandez D, Cummings D, Edwards F, Shear J, Schmidt C
J Mater Chem B
. 2020 Apr;
3(25):5001-5004.
PMID: 32262453
We report the application of multiphoton microfabrication to prepare conducting polymer (CP)-based biomaterials that were capable of drug delivery and interacting with brain tissue ex vivo, thereby highlighting the potential...
4.
Simoska O, Sans M, Eberlin L, Shear J, Stevenson K
Biosens Bioelectron
. 2019 Aug;
142:111538.
PMID: 31376710
The opportunistic human pathogen Pseudomonas aeruginosa (Pa) causes several infections acquired in a healthcare setting. During initial stages of infection, Pa produces redox-active phenazine metabolites, including pyocyanin (PYO), 5-methylphenazine-1-carboxylic acid...
5.
Simoska O, Sans M, Fitzpatrick M, Crittenden C, Eberlin L, Shear J, et al.
ACS Sens
. 2018 Dec;
4(1):170-179.
PMID: 30525472
Here, we use a recently developed electrochemical sensing platform of transparent carbon ultramicroelectrode arrays (T-CUAs) for the in vitro detection of phenazine metabolites from the opportunistic human pathogen Pseudomonas aeruginosa....
6.
Hernandez D, Ritschdorff E, Connell J, Shear J
J Am Chem Soc
. 2018 Oct;
140(43):14064-14068.
PMID: 30350959
In their native environments, adherent cells encounter dynamic topographical cues involved in promoting differentiation, orientation, and migration. Ideally, such processes would be amenable to study in cell culture using tools...
7.
Crittenden C, Morrison L, Fitzpatrick M, Myers A, Novelli E, Rosenberg J, et al.
Analyst
. 2018 Jul;
143(15):3607-3618.
PMID: 29968868
Cationic antimicrobial peptides (CAMPs) have been known to act as multi-modal weapons against Gram-negative bacteria. As a new approach to investigate the nature of the interactions between CAMPs and the...
8.
Darch S, Simoska O, Fitzpatrick M, Barraza J, Stevenson K, Bonnecaze R, et al.
Proc Natl Acad Sci U S A
. 2018 Apr;
115(18):4779-4784.
PMID: 29666244
Quorum sensing (QS) is a bacterial communication system that involves production and sensing of extracellular signals. In laboratory models, QS allows bacteria to monitor and respond to their own cell...
9.
Elliott J, Simoska O, Karasik S, Shear J, Stevenson K
Anal Chem
. 2017 May;
89(12):6285-6289.
PMID: 28558232
Pyocyanin is a virulence factor produced as a secondary metabolite by the opportunistic human pathogen, Pseudomonas aeruginosa. Fast and direct detection of pyocyanin is of importance as it could provide...
10.
Elliott J, Duay J, Simoska O, Shear J, Stevenson K
Anal Chem
. 2016 Dec;
89(2):1267-1274.
PMID: 27989112
Transparent carbon ultramicroelectrode arrays (T-CUAs) were made using a previously reported facile fabrication method (Duay et al. Anal. Chem. 2015, 87, 10109). Two modifications introduced to the T-CUAs were examined...