Jasmin Fettel
Overview
Explore the profile of Jasmin Fettel including associated specialties, affiliations and a list of published articles.
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6
Citations
67
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0
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Recent Articles
1.
Piesche M, Roos J, Kuhn B, Fettel J, Hellmuth N, Brat C, et al.
Front Pharmacol
. 2020 Oct;
11:1297.
PMID: 33013366
Nitro fatty acids (NFAs) are endogenously generated lipid mediators deriving from reactions of unsaturated electrophilic fatty acids with reactive nitrogen species. Furthermore, Mediterranean diets can be a source of NFA....
2.
Fettel J, Kuhn B, Guillen N, Surun D, Peters M, Bauer R, et al.
FASEB J
. 2018 Sep;
33(2):1711-1726.
PMID: 30188757
Sphingosine-1-phosphate (S1P) is involved in the regulation of important cellular processes, including immune-cell trafficking and proliferation. Altered S1P signaling is strongly associated with inflammation, cancer progression, and atherosclerosis; however, the...
3.
Kuhn B, Brat C, Fettel J, Hellmuth N, Maucher I, Bulut U, et al.
Biochem Pharmacol
. 2018 Jun;
155:48-60.
PMID: 29909078
Nitro-fatty acids (NFAs) are endogenously occurring lipid mediators exerting strong anti-inflammatory effects and acting as anti-oxidants in a number of animal models of inflammation. These NFA effects are mediated by...
4.
Roos J, Peters M, Maucher I, Kuhn B, Fettel J, Hellmuth N, et al.
Antioxid Redox Signal
. 2017 Jul;
28(14):1265-1285.
PMID: 28699354
Aims: 5-Lipoxygenase (5-LO) is the key enzyme of leukotriene (LT) biosynthesis and is critically involved in a number of inflammatory diseases such as arthritis, gout, bronchial asthma, atherosclerosis, and cancer....
5.
Maucher I, Ruhl M, Kretschmer S, Hofmann B, Kuhn B, Fettel J, et al.
Biochem Pharmacol
. 2016 Nov;
125:55-74.
PMID: 27823964
Recently, we published that nitro-fatty acids (NFA) are potent electrophilic molecules which inhibit 5-lipoxygenase (5-LO) by interacting catalytically with cysteine residues next to a substrate entry channel. The electrophilicity is...
6.
Roos J, Grosch S, Werz O, Schroder P, Ziegler S, Fulda S, et al.
Pharmacol Ther
. 2015 Nov;
157:43-64.
PMID: 26549540
Canonical Wnt signaling is a highly conserved pathway with a prominent role in embryogenic development, adult tissue homeostasis, cell polarization, stem cell biology, cell differentiation, and proliferation. Furthermore, canonical Wnt...