Jasmin C Aschenbrenner
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Explore the profile of Jasmin C Aschenbrenner including associated specialties, affiliations and a list of published articles.
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5
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34
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Recent Articles
1.
Aschenbrenner J, de Godoy A, Fairhead M, Tomlinson C, Winokan M, Balcomb B, et al.
bioRxiv
. 2024 Sep;
PMID: 39229067
Chikungunya virus (CHIKV) causes severe fever, rash and debilitating joint pain that can last for monthsor even years. Millions of people have been infected with CHIKV, mostly in low and...
2.
Lee A, Amick I, Aschenbrenner J, Barr H, Benjamin J, Brandis A, et al.
bioRxiv
. 2024 Sep;
PMID: 39229055
A strategy for pandemic preparedness is the development of antivirals against a wide set of viral targets with complementary mechanisms of action. SARS-CoV-2 nsp3-mac1 is a viral macrodomain with ADP-ribosylhydrolase...
3.
Boby M, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson M, et al.
Science
. 2023 Nov;
382(6671):eabo7201.
PMID: 37943932
We report the results of the COVID Moonshot, a fully open-science, crowdsourced, and structure-enabled drug discovery campaign targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease. We discovered...
4.
Ebrecht A, Aschenbrenner J, Smit M, Opperman D
Org Biomol Chem
. 2020 Dec;
19(2):439-445.
PMID: 33331366
Biocatalysts are receiving increased attention in the field of selective oxyfunctionalization of C-H bonds, with cytochrome P450 monooxygenases (CYP450s), and the related peroxygenases, leading the field. Here we report on...
5.
Marijanovic E, Weronika Swiderska K, Andersen J, Aschenbrenner J, Webb C, Drag M, et al.
Biochem J
. 2020 Sep;
477(19):3819-3832.
PMID: 32926129
Toxoplasmosis is a parasitic disease caused by infection with Toxoplasma gondii that currently has few therapeutic options. The M1 aminopeptidase enzymes have been shown to be attractive targets for anti-parasitic...