Jasbir S Arora
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Explore the profile of Jasbir S Arora including associated specialties, affiliations and a list of published articles.
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11
Citations
126
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Recent Articles
1.
Arora J, Oe T, Blair I
J Labelled Comp Radiopharm
. 2014 Aug;
54(5):247-251.
PMID: 25152561
Lipid hydroperoxides undergo homolytic decomposition into the bifunctional 4-hydroxy-2()-nonenal and 4-oxo-2()-nonenal (ONE). These bifunctional electrophiles are highly reactive and can readily modify intracellular molecules including glutathione (GSH), deoxyribonucleic acid (DNA)...
2.
Hammons A, Summers C, Jochems J, Arora J, Zhang S, Blair I, et al.
Eur J Pharmacol
. 2012 Sep;
696(1-3):12-7.
PMID: 22975265
Elevated homocysteine is a risk marker for several major human pathologies. Emerging evidence suggests that perturbations of folate/homocysteine metabolism can directly modify production of inflammatory mediators. Pemetrexed acts by inhibiting...
3.
Mesaros C, Arora J, Wholer A, Vachani A, Blair I
Free Radic Biol Med
. 2012 May;
53(3):610-7.
PMID: 22613262
7,8-Dihydro-8-oxo-2'-deoxyguanosine (8-oxo-dGuo) is a useful biomarker of oxidative stress. However, its analysis can be challenging because 8-oxo-dGuo must be quantified in the presence of dGuo, without artifactual conversion to 8-oxo-dGuo....
4.
Liu X, Zhang S, Arora J, Snyder N, Shah S, Blair I
Chem Res Toxicol
. 2011 Sep;
24(12):2227-36.
PMID: 21916491
Previously, we established that 11(R)-hydroxy-5,8,12,14-(Z,Z,E,Z)-eicosatetraenoic acid (HETE) was a significant cyclooxygenase (COX)-2-derived arachidonic acid (AA) metabolite in epithelial cells. Stable isotope dilution chiral liquid chromatography (LC)-electron capture atmospheric pressure chemical...
5.
Xiang Y, Arora J, Abdel-Malek K
J Biomech
. 2010 Nov;
44(4):683-93.
PMID: 21092968
An optimization-based formulation and solution method are presented to predict asymmetric human gait for a large-scale skeletal model. Predictive dynamics approach is used in which both the joint angles and...
6.
Kim H, Wang Q, Rahmatalla S, Swan C, Arora J, Abdel-Malek K, et al.
J Biomech Eng
. 2008 Jun;
130(3):031002.
PMID: 18532851
Since humans can walk with an infinite variety of postures and limb movements, there is no unique solution to the modeling problem to predict human gait motions. Accordingly, we test...
7.
Jian W, Arora J, Oe T, Shuvaev V, Blair I
Free Radic Biol Med
. 2005 Oct;
39(9):1162-76.
PMID: 16214032
Endothelial dysfunction is considered to be the earliest event in atherogenesis. Oxidative stress, inflammation, and apoptosis play critical roles in its progression and onset. Lipid peroxidation, which occurs during oxidative...
8.
Jian W, Lee S, Arora J, Elipe M, Blair I
Chem Res Toxicol
. 2005 Mar;
18(3):599-610.
PMID: 15777099
Analysis of products from the reaction between 5(S)-hydroperoxy-6,8,11,14-(E,Z,Z,Z)-eicosatetraenoic acid and 2'-deoxyguanosine in the presence of FeII, FeIII, or vitamin C by liquid chromatography/atmospheric pressure chemical ionization/mass spectrometry revealed the presence...
9.
Lee S, Elipe M, Arora J, Blair I
Chem Res Toxicol
. 2005 Mar;
18(3):566-78.
PMID: 15777096
It has been proposed that 13(S)-hydroperoxy-9Z,11E-octadecadienoic acid [13(S)-HPODE]-mediated formation of 4-oxo-2(E)-nonenal and 4-hydroxy-2(E)-nonenal arises from a Hock rearrangement. This suggested that a 4-oxo-2(E)-nonenal-related molecule, 9,12-dioxo-10(E)-dodecenoic acid (DODE), could also result...
10.
Lee S, Oe T, Arora J, Blair I
J Mass Spectrom
. 2005 Mar;
40(5):661-8.
PMID: 15739161
Intracellular Fe(II), which is up-regulated during oxidative stress and during iron overload, induces the formation of a hydroxyl radical by Fenton chemistry. The hydroxyl radical can convert the prototypic omega-6...