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Jared Feldman

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Citations 7766
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Recent Articles
1.
Feldman J, Ramos A, Vu M, Maurer D, Rosado V, Lingwood D, et al.
Sci Immunol . 2025 Jan; 10(103):eado9572. PMID: 39854479
Understanding the naïve B cell repertoire and its specificity for potential zoonotic threats, such as the highly pathogenic avian influenza (HPAI) H5Nx viruses, may allow prediction of infection- or vaccine-specific...
2.
Wamhoff E, Ronsard L, Feldman J, Knappe G, Hauser B, Romanov A, et al.
Nat Commun . 2024 Jan; 15(1):795. PMID: 38291019
Protein-based virus-like particles (P-VLPs) are commonly used to spatially organize antigens and enhance humoral immunity through multivalent antigen display. However, P-VLPs are thymus-dependent antigens that are themselves immunogenic and can...
3.
Curtis N, Shin S, Hederman A, Connor R, Wieland-Alter W, Ionov S, et al.
bioRxiv . 2023 Sep; PMID: 37745524
While our understanding of SARS-CoV-2 pathogenesis and antibody responses following infection and vaccination has improved tremendously since the outbreak in 2019, the sequence identities and relative abundances of the individual...
4.
Ronsard L, Yousif A, Nait Mohamed F, Feldman J, Okonkwo V, McCarthy C, et al.
Nat Commun . 2023 Aug; 14(1):5249. PMID: 37640732
Low affinity is common for germline B cell receptors (BCR) seeding development of broadly neutralizing antibodies (bnAbs) that engage hypervariable viruses, including HIV. Antibody affinity selection is also non-homogenizing, insuring...
5.
Wuo M, Dugan A, Halim M, Hauser B, Feldman J, Caradonna T, et al.
ACS Cent Sci . 2023 May; 9(5):947-956. PMID: 37252360
Enveloped viruses co-opt host glycosylation pathways to decorate their surface proteins. As viruses evolve, emerging strains can modify their glycosylation patterns to influence host interactions and subvert immune recognition. Still,...
6.
Gnanaprakasam R, Keller M, Glassman R, El-Khoury M, Chen D, Feola N, et al.
J Med Virol . 2023 Mar; 95(4):e28699. PMID: 36951318
Early in the 2022 Mpox (MPX) global outbreak, caseloads in the New York Metropolitan area climbed rapidly before other US urban areas. This case series summarizes the authors' clinical experience...
7.
Nanishi E, Borriello F, Seo H, OMeara T, McGrath M, Saito Y, et al.
NPJ Vaccines . 2023 Mar; 8(1):30. PMID: 36869134
No abstract available.
8.
Nanishi E, Borriello F, Seo H, OMeara T, McGrath M, Saito Y, et al.
NPJ Vaccines . 2023 Feb; 8(1):18. PMID: 36788219
Development of SARS-CoV-2 vaccines that protect vulnerable populations is a public health priority. Here, we took a systematic and iterative approach by testing several adjuvants and SARS-CoV-2 antigens to identify...
9.
Hauser B, Feldman J, Sangesland M, Ronsard L, Denis K, Sheehan M, et al.
Cell Rep Med . 2022 Nov; 3(12):100834. PMID: 36423634
The emergence of the antigenically distinct and highly transmissible Omicron variant highlights the possibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immune escape due to viral evolution. This continued...
10.
Caradonna T, Ronsard L, Yousif A, Windsor I, Hecht R, Bracamonte-Moreno T, et al.
Cell Rep . 2022 Nov; 41(6):111628. PMID: 36351401
Pathogens evade host humoral responses by accumulating mutations in surface antigens. While variable, there are conserved regions that cannot mutate without compromising fitness. Antibodies targeting these conserved epitopes are often...