Janusz Aleksander Siedlecki
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Explore the profile of Janusz Aleksander Siedlecki including associated specialties, affiliations and a list of published articles.
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15
Citations
164
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Recent Articles
1.
Mossakowska B, Fabisiewicz A, Tudek B, Siedlecki J
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499013
Photodynamic therapy (PDT) is a low-invasive treatment method that can be used to treat VIN patients. A photosensitizer (PS) applied to a patient is activated with use of the appropriate...
2.
Mossakowska B, Shahmoradi Ghahe S, Cysewski D, Fabisiewicz A, Tudek B, Siedlecki J
Int J Mol Sci
. 2022 Apr;
23(8).
PMID: 35456936
Photodynamic therapy (PDT) is a valuable treatment method for vulvar intraepithelial neoplasia (VIN). It allows for the treatment of a multifocal disease with minimal tissue destruction. 5-Aminolevulinic acid (5-ALA) is...
3.
Kober P, Boresowicz J, Rusetska N, Maksymowicz M, Goryca K, Kunicki J, et al.
Mol Cell Endocrinol
. 2018 Feb;
473:194-204.
PMID: 29410024
Nonfunctioning pituitary adenomas (NFPAs) are among the most frequent intracranial tumors but their molecular background, including changes in epigenetic regulation, remains poorly understood. We performed genome-wide DNA methylation profiling of...
4.
Bujko M, Kober P, Statkiewicz M, Mikula M, Grecka E, Rusetska N, et al.
Int J Oncol
. 2017 Jul;
51(3):841-850.
PMID: 28713969
Tyrosine phosphorylation is one of the basic mechanisms for signal transduction in the cell. Receptors exhibiting tyrosine kinase activity are widely involved in carcinogenesis and are negatively regulated by receptor...
5.
Bujko M, Kober P, Mikula M, Ligaj M, Ostrowski J, Siedlecki J
Oncol Lett
. 2015 Jul;
9(6):2463-2470.
PMID: 26137091
Epithelial tissues achieve a highly organized structure due to cell-cell junction complexes. Carcinogenesis is accompanied by changes in cell interactions and tissue morphology, which appear in the early stages of...
6.
Bujko M, Kober P, Statkiewicz M, Mikula M, Ligaj M, Zwierzchowski L, et al.
Gastroenterol Res Pract
. 2015 May;
2015:317093.
PMID: 25972897
Carcinogenesis involves altered cellular interaction and tissue morphology that partly arise from aberrant expression of cadherins. Mucin-like protocadherin is implicated in intercellular adhesion and its expression was found decreased in...
7.
Musialik E, Bujko M, Kober P, Wypych A, Gawle-Krawczyk K, Matysiak M, et al.
Blood Res
. 2015 Apr;
50(1):26-32.
PMID: 25830127
Background: Precursor B-cell acute lymphoblastic leukemia (B-cell ALL) is the most common neoplasm in children and is characterized by genetic and epigenetic aberrations in hematopoietic transcription factor (TF) genes. This...
8.
Musialik E, Bujko M, Kober P, Grygorowicz M, Libura M, Przestrzelska M, et al.
Mol Med Rep
. 2015 Jan;
11(5):3948-54.
PMID: 25585874
HOXA genes encode transcription factors, which are crucial for embryogenesis and tissue differentiation and are involved in the early stages of hematopoiesis. Aberrations in HOXA genes and their cofactor MEIS1...
9.
Bujko M, Kober P, Tysarowski A, Matyja E, Mandat T, Bonicki W, et al.
Oncol Lett
. 2014 Jun;
7(6):2019-2022.
PMID: 24932282
Meningiomas are among the most frequent intracranial tumors. Treatment involves surgical resection with optional subsequent radiotherapy for high-grade meningiomas or radiosurgery following incomplete tumor removal. At present, no pharmacological agents...
10.
Musialik E, Bujko M, Kober P, Grygorowicz M, Libura M, Przestrzelska M, et al.
Leuk Res
. 2014 Jun;
38(7):850-6.
PMID: 24878001
CCAAT/enhancer binding proteins (CEBPs) are transcription factors regulating myeloid differentiation. Disturbances of their expression may contribute to leukemogenesis. In this study we compared promoter methylation and expression levels of selected...