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Janne Makkonen

Explore the profile of Janne Makkonen including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 413
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Recent Articles
1.
Sevastianova K, Santos A, Kotronen A, Hakkarainen A, Makkonen J, Silander K, et al.
Am J Clin Nutr . 2012 Sep; 96(4):727-34. PMID: 22952180
Background: Cross-sectional studies have identified a high intake of simple sugars as an important dietary factor predicting nonalcoholic fatty liver disease (NAFLD). Objective: We examined whether overfeeding overweight subjects with...
2.
Hyysalo J, Stojkovic I, Kotronen A, Hakkarainen A, Sevastianova K, Makkonen J, et al.
J Gastroenterol Hepatol . 2011 Dec; 27(5):951-6. PMID: 22141340
Background And Aim: A recent study in Indian subjects suggested common variants in apolipoprotein C3 (APOC3) (T-455C at rs2854116 and C-482T at rs2854117) to contribute to non-alcoholic fatty liver disease...
3.
Simonen P, Kotronen A, Hallikainen M, Sevastianova K, Makkonen J, Hakkarainen A, et al.
J Hepatol . 2010 Oct; 54(1):153-9. PMID: 20947198
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is associated with impaired glucose and lipoprotein metabolism. However, the metabolism of cholesterol in NAFLD remains unexplored. We investigated how fatty liver...
4.
Makkonen J, Pietilainen K, Rissanen A, Kaprio J, Yki-Jarvinen H
J Hepatol . 2009 Mar; 50(5):1035-42. PMID: 19303161
Background/aims: This study aimed to determine the heritability of serum alanine aminotransferase (S-ALT) and fasting serum insulin (fS-insulin) concentration as well as determine the association of these measures with liver...
5.
Westerbacka J, Corner A, Kolak M, Makkonen J, Turpeinen U, Hamsten A, et al.
Am J Physiol Endocrinol Metab . 2008 Feb; 294(5):E841-5. PMID: 18270300
CCL2 (MCP-1, monocyte chemoattractant protein 1) and CCL3 (MIP-1alpha, macrophage inflammatory protein 1alpha) are required for macrophage infiltration in adipose tissue. Insulin increases CCL2 expression in adipose tissue and in...
6.
Kolak M, Westerbacka J, Velagapudi V, Wagsater D, Yetukuri L, Makkonen J, et al.
Diabetes . 2007 Jul; 56(8):1960-8. PMID: 17620421
Objective: We sought to determine whether adipose tissue is inflamed in individuals with increased liver fat (LFAT) independently of obesity. Research Design And Methods: A total of 20 nondiabetic, healthy,...