Jang Hyun Choi
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Explore the profile of Jang Hyun Choi including associated specialties, affiliations and a list of published articles.
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Articles
68
Citations
5838
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Recent Articles
1.
Wie M, Khim K, Groehler Iv A, Heo S, Woo J, Son K, et al.
NAR Cancer
. 2023 Aug;
5(3):zcad042.
PMID: 37554969
Targeting - and -deficient tumors through synthetic lethality using poly(ADP-ribose) polymerase inhibitors (PARPi) has emerged as a successful strategy for cancer therapy. PARPi monotherapy has shown excellent efficacy and safety...
2.
Jang H, Lee Y, Dao T, Jo Y, Khim K, Eom H, et al.
Exp Mol Med
. 2023 Jul;
55(8):1720-1733.
PMID: 37524868
Autophagy functions in cellular quality control and metabolic regulation. Dysregulation of autophagy is one of the major pathogenic factors contributing to the progression of nonalcoholic fatty liver disease (NAFLD). Autophagy...
3.
Kang Y, Han Y, Khim K, Choi W, Ju M, Park K, et al.
Nucleic Acids Res
. 2023 Jun;
51(15):7936-7950.
PMID: 37378431
Replication protein A (RPA), a eukaryotic single-stranded DNA (ssDNA) binding protein, dynamically interacts with ssDNA in different binding modes and plays essential roles in DNA metabolism such as replication, repair,...
4.
Kwon T, Ra J, Lee S, Baek I, Khim K, Lee E, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(9).
PMID: 35217600
An ideal cancer therapeutic strategy involves the selective killing of cancer cells without affecting the surrounding normal cells. However, researchers have failed to develop such methods for achieving selective cancer...
5.
Lee Y, Jang H, Kim S, Choi S, Khim K, Eom H, et al.
Elife
. 2021 Dec;
10.
PMID: 34964438
Background: Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation and imbalances in lipid metabolism in the liver. Although nuclear receptors (NRs) play a crucial role in hepatic...
6.
Kang H, Eom H, Kim H, Myung K, Kwon H, Choi J
Exp Mol Med
. 2021 Oct;
53(10):1602-1611.
PMID: 34697388
Transcription-replication conflicts lead to DNA damage and genomic instability, which are closely related to human diseases. A major source of these conflicts is the formation of R-loops, which consist of...
7.
Hyun J, Park M, Lee Y, Lee Y, Jeong S, Choi S, et al.
J Ethnopharmacol
. 2021 May;
278:114238.
PMID: 34048878
Ethnopharmacological Relevance: Vernicia fordii (Hemsl.) Airy Shaw (V. fordii) is also known as the tung tree and its leaves and fruit are used as an oriental treatment for dyspepsia, edema,...
8.
Ju M, Shin K, Lee J, Khim K, Lee E, Ra J, et al.
Nucleic Acids Res
. 2021 May;
49(10):5605-5622.
PMID: 33963872
Proper activation of DNA repair pathways in response to DNA replication stress is critical for maintaining genomic integrity. Due to the complex nature of the replication fork (RF), problems at...
9.
Choi J, Lee H, Lee H, Lee H
Int J Mol Sci
. 2021 Apr;
22(6).
PMID: 33802993
Despite advances in the preparation of metal oxide (MO) nanoparticles (NPs) as catalysts for various applications, concerns about the biosafety of these particles remain. In this study, we prepared transition...
10.
Choi J, Hong J, Son Y, Wang J, Kim H, Lee H, et al.
Nanomaterials (Basel)
. 2020 Aug;
10(8).
PMID: 32781774
We demonstrated that Fe/Cr doped and pH-modified CeO nanoparticles (NPs) exhibit enhanced photocatalytic performance as compared to bare CeO NPs, using photocatalytic degradation. To assess the toxicity level of these...