Jang-Eun Cho
Overview
Explore the profile of Jang-Eun Cho including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
787
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0
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Recent Articles
1.
Feng W, Simpson D, Cho J, Carvajal-Garcia J, Smith C, Headley K, et al.
Nucleic Acids Res
. 2021 May;
49(9):5095-5105.
PMID: 33963863
Genome integrity and genome engineering require efficient repair of DNA double-strand breaks (DSBs) by non-homologous end joining (NHEJ), homologous recombination (HR), or alternative end-joining pathways. Here we describe two complementary...
2.
Gusa A, Williams J, Cho J, Floyd Averette A, Sun S, Shouse E, et al.
Proc Natl Acad Sci U S A
. 2020 Apr;
117(18):9973-9980.
PMID: 32303657
When transitioning from the environment, pathogenic microorganisms must adapt rapidly to survive in hostile host conditions. This is especially true for environmental fungi that cause opportunistic infections in immunocompromised patients...
3.
Carvajal-Garcia J, Cho J, Carvajal-Garcia P, Feng W, Wood R, Sekelsky J, et al.
Proc Natl Acad Sci U S A
. 2020 Apr;
117(15):8476-8485.
PMID: 32234782
DNA polymerase theta mediates an end joining pathway (TMEJ) that repairs chromosome breaks. It requires resection of broken ends to generate long, 3' single-stranded DNA tails, annealing of complementary sequence...
4.
Cho J, Jinks-Robertson S
Proc Natl Acad Sci U S A
. 2019 Oct;
116(45):22683-22691.
PMID: 31636207
Topoisomerase I (Top1) resolves supercoils by nicking one DNA strand and facilitating religation after torsional stress has been relieved. During its reaction cycle, Top1 forms a covalent cleavage complex (Top1cc)...
5.
Jin H, Cho J, Park S
Genes Genomics
. 2018 Dec;
41(4):389-395.
PMID: 30506122
Background: Tetraspanin proteins are expressed in various immune cells, and they play an important role in tuberculosis formation. CD53 is a protein in the tetraspanin family that is expressed in...
6.
Cho J, Jinks-Robertson S
Methods Mol Biol
. 2017 Nov;
1703:21-45.
PMID: 29177731
Topoisomerase I (Top1) resolves torsional stress that accumulates during transcription, replication and chromatin remodeling by introducing a transient single-strand break in DNA. The cleavage activity of Top1 has opposing roles,...
7.
Bell J, Cho J, Giffard R
Transl Stroke Res
. 2017 Jun;
8(6):585-596.
PMID: 28646450
Preconditioning is a paradigm in which sublethal stress-prior to a more injurious insult-induces protection against injury. In the central nervous system (CNS), preconditioning against ischemic stroke is induced by short...
8.
Cho J, Jinks-Robertson S
J Mol Biol
. 2016 Aug;
429(21):3156-3167.
PMID: 27511624
High levels of transcription stimulate mutation rates in microorganisms, and this occurs primarily through an enhanced accumulation of DNA damage. The major source of transcription-associated damage in yeast is Topoisomerase...
9.
Cho J, Huang S, Burgers P, Shuman S, Pommier Y, Jinks-Robertson S
Nucleic Acids Res
. 2016 Jun;
44(16):7714-21.
PMID: 27257064
Ribonucleotides are the most abundant non-canonical component of yeast genomic DNA and their persistence is associated with a distinctive mutation signature characterized by deletion of a single repeat unit from...
10.
Cliff J, Cho J, Lee J, Ronacher K, King E, van Helden P, et al.
J Infect Dis
. 2015 Sep;
213(3):485-95.
PMID: 26351358
Background: Currently, there are no tools to accurately predict tuberculosis relapse. This study aimed to determine whether patients who experience tuberculosis relapse have different immune responses to mycobacteria in vitro...