Janet Taggart
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Explore the profile of Janet Taggart including associated specialties, affiliations and a list of published articles.
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9
Citations
118
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Recent Articles
1.
MacDiarmid C, Taggart J, Wang Y, Vashisht A, Qing X, Wohlschlegel J, et al.
bioRxiv
. 2025 Mar;
PMID: 40027620
Zinc (Zn) is an essential nutrient supporting a range of critical processes. In the yeast , Zn deficiency induces a transcriptional response mediated by the Zap1 activator, which controls a...
2.
MacDiarmid C, Taggart J, Kubisiak M, Eide D
J Biol Chem
. 2024 Mar;
300(4):107147.
PMID: 38460940
Zinc is required for many critical processes, including intermediary metabolism. In Saccharomyces cerevisiae, the Zap1 activator regulates the transcription of ∼80 genes in response to Zn supply. Some Zap1-regulated genes...
3.
Tatip S, Taggart J, Wang Y, MacDiarmid C, Eide D
Mol Microbiol
. 2019 Nov;
113(1):285-296.
PMID: 31692084
Changes in RNA are often poor predictors of protein accumulation. One factor disrupting this relationship are changes in transcription start sites (TSSs). Therefore, we explored how alterations in TSS affected...
4.
Wang Y, Weisenhorn E, MacDiarmid C, Andreini C, Bucci M, Taggart J, et al.
Metallomics
. 2018 Oct;
10(12):1755-1776.
PMID: 30358795
Zinc is an essential cofactor for many proteins. A key mechanism of zinc homeostasis during deficiency is "zinc sparing" in which specific zinc-binding proteins are repressed to reduce the cellular...
5.
Taggart J, Wang Y, Weisenhorn E, MacDiarmid C, Russell J, Coon J, et al.
Genes (Basel)
. 2018 Sep;
9(9).
PMID: 30235899
Zinc homeostasis is essential for all organisms. The Zap1 transcriptional activator regulates these processes in the yeast . During zinc deficiency, Zap1 increases expression of zinc transporters and proteins involved...
6.
Bucci M, Weisenhorn E, Haws S, Yao Z, Zimmerman G, Gannon M, et al.
Genetics
. 2018 Jan;
208(3):1115-1130.
PMID: 29321173
The Zap1 transcription factor of is a key regulator in the genomic responses to zinc deficiency. Among the genes regulated by Zap1 during zinc deficiency is the autophagy-related gene Here,...
7.
Taggart J, MacDiarmid C, Haws S, Eide D
Mol Microbiol
. 2017 Oct;
106(5):678-689.
PMID: 28963784
Maintaining zinc homeostasis is an important property of all organisms. In the yeast Saccharomyces cerevisiae, the Zap1 transcriptional activator is a central player in this process. In response to zinc...
8.
Wu Y, Taggart J, Song P, MacDiarmid C, Eide D
PLoS One
. 2016 Sep;
11(9):e0163256.
PMID: 27657924
The Msc2 and Zrg17 proteins of Saccharomyces cerevisiae form a complex to transport zinc into the endoplasmic reticulum. ZRG17 is transcriptionally induced in zinc-limited cells by the Zap1 transcription factor....
9.
MacDiarmid C, Taggart J, Jeong J, Kerdsomboon K, Eide D
J Biol Chem
. 2016 Jul;
291(36):18880-96.
PMID: 27432887
Stability of many proteins requires zinc. Zinc deficiency disrupts their folding, and the ubiquitin-proteasome system may help manage this stress. In Saccharomyces cerevisiae, UBI4 encodes five tandem ubiquitin monomers and...
10.
MacDiarmid C, Taggart J, Kerdsomboon K, Kubisiak M, Panascharoen S, Schelble K, et al.
J Biol Chem
. 2013 Sep;
288(43):31313-27.
PMID: 24022485
Zinc is required for the folding and function of many proteins. In Saccharomyces cerevisiae, homeostatic and adaptive responses to zinc deficiency are regulated by the Zap1 transcription factor. One Zap1...