Janet Rubin
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Explore the profile of Janet Rubin including associated specialties, affiliations and a list of published articles.
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91
Citations
3375
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Recent Articles
1.
Goelzer M, Howard S, Zavala A, Conway D, Rubin J, Uzer G
Commun Biol
. 2025 Mar;
8(1):428.
PMID: 40082539
Critical to the mechano-regulation of mesenchymal stem cells (MSC), Linker of the Nucleoskeleton and Cytoskeleton (LINC) complex transduces cytoskeletal forces to the nuclei. The LINC complex contains outer nuclear membrane...
2.
Nikitina N, Bursa N, Goelzer M, Goldfeldt M, Crandall C, Howard S, et al.
Small Struct
. 2024 Sep;
5(5).
PMID: 39220563
Quantitative and volumetric assessment of filamentous actin fibers (F-actin) remains challenging due to their interconnected nature, leading researchers to utilize threshold based or qualitative measurement methods with poor reproducibility. Here...
3.
Sen B, Xie Z, Thomas M, Pattenden S, Howard S, McGrath C, et al.
Nat Commun
. 2024 May;
15(1):4095.
PMID: 38750021
Polymerized β-actin may provide a structural basis for chromatin accessibility and actin transport into the nucleus can guide mesenchymal stem cell (MSC) differentiation. Using MSC, we show that using CK666...
4.
McGrath C, Little-Letsinger S, Pagnotti G, Sen B, Xie Z, Uzer G, et al.
Obes Facts
. 2024 Jan;
17(2):145-157.
PMID: 38224679
Introduction: Longitudinal effect of diet-induced obesity on bone is uncertain. Prior work showed both no effect and a decrement in bone density or quality when obesity begins prior to skeletal...
5.
Nikitina N, Bursa N, Goelzer M, Goldfeldt M, Crandall C, Howard S, et al.
bioRxiv
. 2023 Apr;
PMID: 37066142
Quantitative and volumetric assessment of filamentous actin fibers (F-actin) remains challenging due to their interconnected nature, leading researchers to utilize threshold based or qualitative measurement methods with poor reproducibility. Here...
6.
Rubin J, Styner M
Exp Biol Med (Maywood)
. 2022 Aug;
247(24):2213-2222.
PMID: 35983849
All organisms exist within a physical space and respond to physical forces as part of daily life. In higher organisms, the skeleton is critical for locomotion in the physical environment,...
7.
Sen B, Xie Z, Howard S, Styner M, van Wijnen A, Uzer G, et al.
Stem Cells
. 2022 Mar;
40(4):423-434.
PMID: 35278073
Mesenchymal stem cells (MSCs) respond to environmental forces with both cytoskeletal re-structuring and activation of protein chaperones of mechanical information, β-catenin, and yes-associated protein 1 (YAP1). To function, MSCs must...
8.
McGrath C, Little-Letsinger S, Sankaran J, Sen B, Xie Z, Styner M, et al.
Front Endocrinol (Lausanne)
. 2022 Feb;
12:782194.
PMID: 35145475
Exercise, typically beneficial for skeletal health, has not yet been studied in lipodystrophy, a condition characterized by paucity of white adipose tissue, with eventual diabetes, and steatosis. We applied a...
9.
Rubin J, van Wijnen A, Uzer G
Nucleus
. 2022 Feb;
13(1):35-48.
PMID: 35133922
There is growing appreciation that architectural components of the nucleus regulate gene accessibility by altering chromatin organization. While nuclear membrane connector proteins link the mechanosensitive actin cytoskeleton to the nucleoskeleton,...
10.
Brozowski J, Timoshchenko R, Serafin D, Allyn B, Koontz J, Rabjohns E, et al.
Stem Cell Res Ther
. 2022 Jan;
13(1):37.
PMID: 35093170
Background: The bone marrow niche supports hematopoietic cell development through intimate contact with multipotent stromal mesenchymal stem cells; however, the intracellular signaling, function, and regulation of such supportive niche cells...