Janet F Partridge
Overview
Explore the profile of Janet F Partridge including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
37
Citations
1600
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Mittal P, Myers J, Carter R, Radko-Juettner S, Malone H, Rosikiewicz W, et al.
Nat Commun
. 2024 Aug;
15(1):7303.
PMID: 39181868
Genes encoding subunits of SWI/SNF (BAF) chromatin remodeling complexes are mutated in nearly 25% of cancers. To gain insight into the mechanisms by which SWI/SNF mutations drive cancer, we contributed...
2.
Radko-Juettner S, Yue H, Myers J, Carter R, Robertson A, Mittal P, et al.
Nature
. 2024 Apr;
629(8012):E12.
PMID: 38684813
No abstract available.
3.
Radko-Juettner S, Yue H, Myers J, Carter R, Robertson A, Mittal P, et al.
Nature
. 2024 Mar;
628(8007):442-449.
PMID: 38538798
Whereas oncogenes can potentially be inhibited with small molecules, the loss of tumour suppressors is more common and is problematic because the tumour-suppressor proteins are no longer present to be...
4.
Zhu Z, Chen X, Guo A, Manzano T, Walsh P, Wills K, et al.
Nature
. 2023 May;
618(7963):180-187.
PMID: 37225980
For cells to initiate and sustain a differentiated state, it is necessary that a 'memory' of this state is transmitted through mitosis to the daughter cells. Mammalian switch/sucrose non-fermentable (SWI/SNF)...
5.
Drosos Y, Myers J, Xu B, Mathias K, Beane E, Radko-Juettner S, et al.
Mol Cell
. 2022 May;
82(13):2472-2489.e8.
PMID: 35537449
Disruption of antagonism between SWI/SNF chromatin remodelers and polycomb repressor complexes drives the formation of numerous cancer types. Recently, an inhibitor of the polycomb protein EZH2 was approved for the...
6.
Yadav R, Matsuda A, Lowe B, Hiraoka Y, Partridge J
Microorganisms
. 2021 Sep;
9(9).
PMID: 34576871
Telomeres play important roles in safeguarding the genome. The specialized repressive chromatin that assembles at telomeres and subtelomeric domains is key to this protective role. However, in many organisms, the...
7.
Lowe B, Yadav R, Henry R, Schreiner P, Matsuda A, Fernandez A, et al.
Elife
. 2021 Feb;
10.
PMID: 33522486
Sequencing of cancer genomes has identified recurrent somatic mutations in histones, termed oncohistones, which are frequently poorly understood. Previously we showed that fission yeast expressing only the H3.3G34R mutant identified...
8.
Lowe B, Maxham L, Hamey J, Wilkins M, Partridge J
Cancers (Basel)
. 2019 May;
11(5).
PMID: 31086012
In this review, we describe the attributes of histone H3 mutants identified in cancer. H3 mutants were first identified in genes encoding H3.3, in pediatric high-grade glioma, and subsequently in...
9.
Yadav R, Jablonowski C, Fernandez A, Lowe B, Henry R, Finkelstein D, et al.
Elife
. 2017 Jul;
6.
PMID: 28718400
Recurrent somatic mutations of in aggressive pediatric high-grade gliomas generate K27M or G34R/V mutant histone H3.3. H3.3-G34R/V mutants are common in tumors with mutations in p53 and ATRX, an H3.3-specific...
10.
Penkert R, Jones B, Hacker H, Partridge J, Hurwitz J
Cytokine
. 2016 Dec;
91:1-5.
PMID: 27940088
Vitamin A is an essential nutrient for the protection of children from respiratory tract disease. Supplementation with vitamin A is frequently prescribed in the clinical setting, in part to combat...