Jane Osbourn
Overview
Explore the profile of Jane Osbourn including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
243
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0
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Recent Articles
1.
Sammut S, Galson J, Minter R, Sun B, Chin S, De Mattos-Arruda L, et al.
Nat Immunol
. 2024 May;
25(5):916-924.
PMID: 38698238
B cells and T cells are important components of the adaptive immune system and mediate anticancer immunity. The T cell landscape in cancer is well characterized, but the contribution of...
2.
Bullen G, Galson J, Hall G, Villar P, Moreels L, Ledsgaard L, et al.
Front Immunol
. 2021 Jul;
12:678570.
PMID: 34211469
Passive immunization using monoclonal antibodies will play a vital role in the fight against COVID-19. The recent emergence of viral variants with reduced sensitivity to some current antibodies and vaccines...
3.
Galson J, Schaetzle S, Bashford-Rogers R, Raybould M, Kovaltsuk A, Kilpatrick G, et al.
Front Immunol
. 2021 Jan;
11:605170.
PMID: 33384691
Deep sequencing of B cell receptor (BCR) heavy chains from a cohort of 31 COVID-19 patients from the UK reveals a stereotypical naive immune response to SARS-CoV-2 which is consistent...
4.
Chen R, Rajan S, Overstreet M, Hurt E, Thomas S, Muniz-Medina V, et al.
Mol Cancer Ther
. 2020 May;
19(8):1649-1659.
PMID: 32404408
Multiple myeloma is a hematologic cancer that disrupts normal bone marrow function and has multiple lines of therapeutic options, but is incurable as patients ultimately relapse. We developed a novel...
5.
Sun J, Hao W, Fillmore N, Ma H, Springer D, Yu Z, et al.
J Am Heart Assoc
. 2019 Dec;
8(24):e013465.
PMID: 31818212
Background Heart failure is one of the leading causes of death in Western countries, and there is a need for new therapeutic approaches. Relaxin-2 is a peptide hormone that mediates...
6.
Nyborg A, Ward C, Zacco A, Chacko B, Grinberg L, Geoghegan J, et al.
PLoS One
. 2016 Dec;
11(12):e0167935.
PMID: 28002433
Humans and higher primates are unique in that they lack uricase, the enzyme capable of oxidizing uric acid. As a consequence of this enzyme deficiency, humans have high serum uric...
7.
Acharya A, Bingham K, Bradner J, Burke W, Charo R, Cherry J, et al.
Nat Biotechnol
. 2016 Jun;
34(6):666.
PMID: 27281427
No abstract available.
8.
Acharya A, Bingham K, Bradner J, Burke W, Charo R, Cherry J, et al.
Nat Biotechnol
. 2016 Mar;
34(3):276-83.
PMID: 26963550
No abstract available.
9.
Miller M, Geleziunas R, Bianchi E, Lennard S, Hrin R, Zhang H, et al.
Proc Natl Acad Sci U S A
. 2005 Oct;
102(41):14759-64.
PMID: 16203977
HIV-1 entry into cells is mediated by the envelope glycoprotein receptor-binding (gp120) and membrane fusion-promoting (gp41) subunits. The gp41 heptad repeat 1 (HR1) domain is the molecular target of the...
10.
Osbourn J, Groves M, Vaughan T
Methods
. 2005 Apr;
36(1):61-8.
PMID: 15848075
Guided selection is a method of producing a human version of a rodent or any other non-human antibody. The process is a serial transition from rodent to human via rodent-human...