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Jan W A Smit

Explore the profile of Jan W A Smit including associated specialties, affiliations and a list of published articles. Areas
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Articles 65
Citations 1392
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Recent Articles
1.
Rabold K, Zoodsma M, Grondman I, Kuijpers Y, Bremmers M, Jaeger M, et al.
Nat Commun . 2022 Oct; 13(1):6149. PMID: 36257966
Myeloid cells, crucial players in antitumoral defense, are affected by tumor-derived factors and treatment. The role of myeloid cells and their progenitors prior to tumor infiltration is poorly understood. Here...
2.
Rops M, Moorlag S, van Deuren R, Jaeger M, Joosten L, Medici M, et al.
Arch Endocrinol Metab . 2022 Jun; 66(4):472-480. PMID: 35657122
Introduction: This study aimed to evaluate the incidence, severity and presence of symptoms of respiratory tract infections and COVID-19, in patients with pre-existing thyroid dysfunction compared to individuals without thyroid...
3.
Crezee T, Tesselaar M, Jaeger M, Rabold K, Corver W, Morreau H, et al.
Oncol Lett . 2021 Jun; 22(2):590. PMID: 34149901
Differentiated thyroid cancer (DTC) is the most frequent endocrine tumor with a good prognosis after primary treatment in most cases. By contrast, 30-40% of patients with metastatic DTC are unresponsive...
4.
Grondman I, de Nooijer A, Antonakos N, Janssen N, Mouktaroudi M, Leventogiannis K, et al.
J Clin Endocrinol Metab . 2021 Mar; 106(7):1994-2009. PMID: 33713408
Context: Lymphopenia is a key feature of immune dysfunction in patients with bacterial sepsis and coronavirus disease 2019 (COVID-19) and is associated with poor clinical outcomes, but the cause is...
5.
Crezee T, Tesselaar M, Nagarajah J, Corver W, Morreau J, Pritchard C, et al.
Cell Oncol (Dordr) . 2021 Feb; 44(3):611-625. PMID: 33534128
Purpose: Non-medullary thyroid cancer (NMTC) treatment is based on the ability of thyroid follicular cells to accumulate radioactive iodide (RAI). However, in a subset of NMTC patients tumor dedifferentiation occurs,...
6.
Crezee T, Petrulea M, Piciu D, Jaeger M, Smit J, Plantinga T, et al.
Endocr Connect . 2020 Oct; 9(11):1065-1074. PMID: 33112820
The PI3K-Akt-mTOR pathway plays a central role in the development of non-medullary thyroid carcinoma (NMTC). Although somatic mutations have been identified in these genes in NMTC patients, the role of...
7.
Hugen N, Sloot Y, Netea-Maier R, van de Water C, Smit J, Nagtegaal I, et al.
J Clin Endocrinol Metab . 2019 Oct; 105(3). PMID: 31641763
Background: Metastatic disease is the main cause of cancer-related mortality in thyroid carcinoma (TC) patients. Clinical studies have suggested differences in metastatic patterns between the different subtypes of TC. This...
8.
Bizino M, Jazet I, Westenberg J, van Eyk H, Paiman E, Smit J, et al.
Cardiovasc Diabetol . 2019 Aug; 18(1):101. PMID: 31399033
Following publication of the original article [1], the authors reported an error in Fig. 3. The bars in the upper right panel that represent heart rate in placebo treated patients...
9.
Bizino M, Jazet I, Westenberg J, van Eyk H, Paiman E, Smit J, et al.
Cardiovasc Diabetol . 2019 May; 18(1):55. PMID: 31039778
Background: Liraglutide is an antidiabetic agent with cardioprotective effect. The purpose of this study is to test efficacy of liraglutide to improve diabetic cardiomyopathy in patients with diabetes mellitus type...
10.
Rabold K, Gielen P, Kers-Rebel E, Netea M, Smit J, Adema G, et al.
Oncologist . 2019 Jan; 24(3):e106-e110. PMID: 30606882
Background: Aggressive forms of thyroid carcinoma (TC) show an abundant infiltration of immune cells, and this correlates with prognosis. However, little is known about circulating immune cell levels in advanced...