Jan W A Smit
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Explore the profile of Jan W A Smit including associated specialties, affiliations and a list of published articles.
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65
Citations
1392
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Recent Articles
11.
Mols F, Schoormans D, Smit J, Netea-Maier R, Links T, van der Graaf W, et al.
Head Neck
. 2018 May;
40(10):2235-2245.
PMID: 29756245
Background: The purpose of this study was to compare general health-related quality of life (HR-QOL) of thyroid cancer survivors with a normative sample stratified by age at diagnosis (adolescents and...
12.
Roerink S, Wagenmakers M, Langenhuijsen J, Ballak D, Rooijackers H, dAncona F, et al.
Obesity (Silver Spring)
. 2017 Jun;
25(8):1369-1374.
PMID: 28594137
Objective: To analyze changes in fat cell size, macrophage infiltration, and local adipose tissue adipokine profiles in different fat depots in patients with active Cushing's syndrome. Methods: Subcutaneous (SC) and...
13.
Stott D, Rodondi N, Kearney P, Ford I, Westendorp R, Mooijaart S, et al.
N Engl J Med
. 2017 Apr;
376(26):2534-2544.
PMID: 28402245
Background: The use of levothyroxine to treat subclinical hypothyroidism is controversial. We aimed to determine whether levothyroxine provided clinical benefits in older persons with this condition. Methods: We conducted a...
14.
Stott D, Gussekloo J, Kearney P, Rodondi N, Westendorp R, Mooijaart S, et al.
BMC Endocr Disord
. 2017 Feb;
17(1):6.
PMID: 28158982
Background: Subclinical hypothyroidism (SCH) is a common condition in elderly people, defined as elevated serum thyroid-stimulating hormone (TSH) with normal circulating free thyroxine (fT4). Evidence is lacking about the effect...
15.
Schneider T, de Wit D, Links T, van Erp N, van der Hoeven J, Gelderblom H, et al.
J Clin Endocrinol Metab
. 2016 Nov;
102(2):698-707.
PMID: 27870581
Background: Mammalian target of rapamycin (mTOR) upregulation has been reported to be involved in the pathogenesis of thyroid tumors, and treatment with the mTOR inhibitor everolimus has shown promising results...
16.
Roerink S, Coolen L, Schenning M, Husson O, Smit J, Marres H, et al.
Head Neck
. 2016 Nov;
39(2):260-268.
PMID: 27859810
Background: Shoulder complaints are frequently reported after surgical treatment for thyroid carcinoma. However, no specific literature on this topic is available for these patients and, hence, its impact on quality...
17.
Lucassen E, Coomans C, van Putten M, de Kreij S, van Genugten J, Sutorius R, et al.
Curr Biol
. 2016 Jul;
26(14):1843-53.
PMID: 27426518
Circadian rhythms are deeply rooted in the biology of virtually all organisms. The pervasive use of artificial lighting in modern society disrupts circadian rhythms and can be detrimental to our...
18.
Schneider T, Kapiteijn E, van Wezel T, Smit J, van der Hoeven J, Morreau H
BMC Cancer
. 2016 Jan;
16:31.
PMID: 26786320
Background: Sorafenib is an orally active multikinase tyrosine kinase inhibitor (TKI) that targets B-type Raf kinase (BRAF), vascular endothelial growth factor receptors (VEGFR) 1 and 2, and rearranged during transfection...
19.
Heinhuis B, Plantinga T, Semango G, Kusters B, Netea M, Dinarello C, et al.
Carcinogenesis
. 2015 Dec;
37(2):197-205.
PMID: 26678222
Alternative splicing is a biological mechanism that enables the synthesis of several isoforms with different or even opposite functions. This process must be tightly regulated to prevent unwanted isoform expression...
20.
Bizino M, Sala M, de Heer P, van der Tol P, Smit J, Webb A, et al.
Magn Reson Imaging Clin N Am
. 2014 Dec;
23(1):41-58.
PMID: 25476673
The metabolic syndrome (MetS) is characterized by ectopic lipid accumulation. Magnetic resonance (MR) imaging and spectroscopy can quantify ectopic lipid accumulation. Consequences of MetS can be evaluated with MR on...