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Jan Schuemann

Explore the profile of Jan Schuemann including associated specialties, affiliations and a list of published articles. Areas
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Articles 81
Citations 1113
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Recent Articles
1.
Rothwell B, Bertolet A, Schuemann J
Radiother Oncol . 2025 Feb; 206:110803. PMID: 39993600
No abstract available.
2.
Wehrenberg-Klee E, An T, Heidari P, Huesa-Berral C, Dreher M, Eldridge A, et al.
Radiology . 2025 Feb; 314(2):e240331. PMID: 39964268
Background External beam radiation therapy for primary and secondary pulmonary malignancies has limited utility for treating ultracentral tumors (ie, adjacent to the proximal bronchial tree or heart) or multiple metastases...
3.
Quintana J, Jiang F, Kang M, Valladolid Onecha V, Konik A, Qin L, et al.
J Nucl Med . 2025 Jan; 66(1):91-97. PMID: 39753366
Radionuclides used for imaging and therapy can show high molecular specificity in the body with appropriate targeting ligands. We hypothesized that local energy delivered by molecularly targeted radionuclides could chemically...
4.
Shin W, D-Kondo J, Ramos-Mendez J, LaVerne J, Rothwell B, Bertolet A, et al.
Phys Med Biol . 2024 Dec; 70(1). PMID: 39657326
TOPAS-nBio enables users to simulate dose rate-dependent radiation chemical yields in water radiolysis accounting for inter-track and long-term chemistry for pulsed irradiation. This study aims to extend the TOPAS-nBio chemistry...
5.
Rothwell B, Bertolet A, Schuemann J
Radiother Oncol . 2024 Nov; 202:110623. PMID: 39528113
Background And Purpose: Proton arc therapy and FLASH radiotherapy (FLASH-RT) each offer unique advantages in proton therapy. However, clinical translation of FLASH-RT faces challenges in defining and delivering high dose...
6.
Kunz L, Bosque J, Nikmaneshi M, Chamseddine I, Munn L, Schuemann J, et al.
Bull Math Biol . 2024 Oct; 86(12):139. PMID: 39460828
Computational models of tumor growth are valuable for simulating the dynamics of cancer progression and treatment responses. In particular, agent-based models (ABMs) tracking individual agents and their interactions are useful...
7.
D-Kondo N, Masilela T, Shin W, Faddegon B, LaVerne J, Schuemann J, et al.
Phys Med Biol . 2024 Oct; 69(21). PMID: 39413818
To present and validate a method to simulate from first principles the effect of oxygen on radiation-induced double-strand breaks (DSBs) using the Monte Carlo Track-structure code TOPAS-nBio.Two chemical models based...
8.
Chamseddine I, Shah K, Lee H, Ehret F, Schuemann J, Bertolet A, et al.
Clin Cancer Res . 2024 Aug; 30(19):4424-4433. PMID: 39106090
Purpose: In radiotherapy (RT) for brain tumors, patient heterogeneity masks treatment effects, complicating the prediction and mitigation of radiation-induced brain necrosis. Therefore, understanding this heterogeneity is essential for improving outcome...
9.
Quintana J, Kang M, Hu H, Ng T, Wojtkiewicz G, Scott E, et al.
ACS Cent Sci . 2024 Jul; 10(7):1371-1382. PMID: 39071065
Radiotherapy is commonly used to treat cancer, and localized energy deposited by radiotherapy has the potential to chemically uncage prodrugs; however, it has been challenging to demonstrate prodrug activation that...
10.
Bobic M, Huesa-Berral C, Terry J, Kunz L, Schuemann J, Fisher D, et al.
Phys Med Biol . 2024 Jul; 69(16). PMID: 39053508
To investigate different dosimetric aspects ofY-IsoPet™ intratumoral therapy in canine soft tissue sarcomas, model the spatial spread of the gel post-injection, evaluate absorbed dose to clinical target volumes, and assess...