Jan O Secher
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Explore the profile of Jan O Secher including associated specialties, affiliations and a list of published articles.
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5
Citations
28
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Recent Articles
1.
Li D, Secher J, Juhl M, Mashayekhi K, Nielsen T, Holst B, et al.
Cell Cycle
. 2017 Apr;
16(11):1070-1084.
PMID: 28426281
Previous research has shown that a subpopulation of cells within cultured human dermal fibroblasts, termed multilineage-differentiating stress enduring (Muse) cells, are preferentially reprogrammed into induced pluripotent stem cells. However, controversy...
2.
Lorenzen E, Follmann F, Secher J, Goericke-Pesch S, Hansen M, Zakariassen H, et al.
Microbes Infect
. 2017 Feb;
19(6):334-342.
PMID: 28189786
Advanced animal models, such as minipigs, are needed for the development of a globally requested human Chlamydia vaccine. Previous studies have shown that vaginal inoculation of sexually mature Göttingen minipigs...
3.
Secher J, Liu Y, Petkov S, Luo Y, Li D, Hall V, et al.
Anim Reprod Sci
. 2017 Jan;
178:40-49.
PMID: 28126267
Porcine somatic cell nuclear transfer (SCNT) has been used extensively to create genetically modified pigs, but the efficiency of the methodology is still low. It has been hypothesized that pluripotent...
4.
Secher J, Ceylan A, Mazzoni G, Mashayekhi K, Li T, Muenthaisong S, et al.
Mol Reprod Dev
. 2017 Jan;
84(3):229-245.
PMID: 28044390
Derivation and stable maintenance of porcine induced pluripotent stem cells (piPSCs) is challenging. We herein systematically analyzed two piPSC lines, derived by lentiviral transduction and cultured under either leukemia inhibitory...
5.
Secher J, Callesen H, Freude K, Hyttel P
Theriogenology
. 2015 Oct;
85(1):162-71.
PMID: 26474684
The quest for porcine pluripotent stem cells (PSCs) was initiated in the early 90s. Initially, it was the intention to benefit from these cells for production of genetically modified pigs...