Jan Moritz Niehues
Overview
Explore the profile of Jan Moritz Niehues including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
118
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Recent Articles
1.
Chatterji S, Niehues J, van Treeck M, Loeffler C, Saldanha O, Veldhuizen G, et al.
NPJ Breast Cancer
. 2023 Nov;
9(1):91.
PMID: 37940649
Breast cancer prognosis and management for both men and women are reliant upon estrogen receptor alpha (ERα) and progesterone receptor (PR) expression to inform therapy. Previous studies have shown that...
2.
Wagner S, Reisenbuchler D, West N, Niehues J, Zhu J, Foersch S, et al.
Cancer Cell
. 2023 Aug;
41(9):1650-1661.e4.
PMID: 37652006
Deep learning (DL) can accelerate the prediction of prognostic biomarkers from routine pathology slides in colorectal cancer (CRC). However, current approaches rely on convolutional neural networks (CNNs) and have mostly...
3.
Muller-Franzes G, Niehues J, Khader F, Arasteh S, Haarburger C, Kuhl C, et al.
Sci Rep
. 2023 Jul;
13(1):12098.
PMID: 37495660
Although generative adversarial networks (GANs) can produce large datasets, their limited diversity and fidelity have been recently addressed by denoising diffusion probabilistic models, which have demonstrated superiority in natural image...
4.
Self-supervised attention-based deep learning for pan-cancer mutation prediction from histopathology
Saldanha O, Loeffler C, Niehues J, van Treeck M, Seraphin T, Hewitt K, et al.
NPJ Precis Oncol
. 2023 Mar;
7(1):35.
PMID: 36977919
The histopathological phenotype of tumors reflects the underlying genetic makeup. Deep learning can predict genetic alterations from pathology slides, but it is unclear how well these predictions generalize to external...
5.
Niehues J, Quirke P, West N, Grabsch H, van Treeck M, Schirris Y, et al.
Cell Rep Med
. 2023 Mar;
4(4):100980.
PMID: 36958327
Deep learning (DL) can predict microsatellite instability (MSI) from routine histopathology slides of colorectal cancer (CRC). However, it is unclear whether DL can also predict other biomarkers with high performance...