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Jan M Werre

Explore the profile of Jan M Werre including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 419
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Recent Articles
1.
Bosman G, Lasonder E, Groenen-Dopp Y, Willekens F, Werre J
J Proteomics . 2012 Jun; 76 Spec No.:203-10. PMID: 22669077
Vesicle formation is an integral part of the physiological erythrocyte aging process. Recent biophysical and immunochemical data have suggested that vesicles originate by the extrusion of membrane patches that, during...
2.
Bosman G, Cluitmans J, Groenen Y, Werre J, Willekens F, Novotny V
Transfusion . 2010 Nov; 51(5):1072-8. PMID: 21077907
Background: During storage of red blood cell (RBCs) before transfusion, RBCs undergo a series of structural and functional changes that include the exposure of phosphatidylserine (PS), a potent removal signal....
3.
Willekens F, Werre J, Groenen-Dopp Y, Roerdinkholder-Stoelwinder B, De Pauw B, Bosman G
Br J Haematol . 2008 Apr; 141(4):549-56. PMID: 18419623
Previous studies demonstrated that 20% of haemoglobin is lost from circulating erythrocytes during their total lifespan by vesiculation. To study whether removal molecules other than membrane-bound haemoglobin were present in...
4.
Bosman G, Willekens F, Werre J
Cell Physiol Biochem . 2005 Aug; 16(1-3):1-8. PMID: 16121027
In physiological circumstances, erythrocyte aging leads to binding of autologous IgG followed by recognition and removal through phagocytosis, mainly by Kupffer cells in the liver. This process is triggered by...
5.
Willekens F, Werre J, Kruijt J, Roerdinkholder-Stoelwinder B, Groenen-Dopp Y, van den Bos A, et al.
Blood . 2004 Nov; 105(5):2141-5. PMID: 15550489
Previous studies have shown that during the lifespan of red blood cells (RBCs) 20% of hemoglobin is lost by shedding of hemoglobin-containing vesicles. However, the fate of these vesicles is...
6.
Willekens F, Roerdinkholder-Stoelwinder B, Groenen-Dopp Y, Bos H, Bosman G, van den Bos A, et al.
Blood . 2002 Oct; 101(2):747-51. PMID: 12393566
Previous studies have shown that approximately 20% of hemoglobin is lost from circulating red blood cells (RBCs), mainly during the second half of the cells' life span. Because hemoglobin-containing vesicles...