Jan Lonzaric
Overview
Explore the profile of Jan Lonzaric including associated specialties, affiliations and a list of published articles.
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5
Citations
153
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Recent Articles
1.
Kackos C, DeBeauchamp J, Davitt C, Lonzaric J, Sealy R, Hurwitz J, et al.
NPJ Vaccines
. 2023 Oct;
8(1):157.
PMID: 37828126
Annually, seasonal influenza is responsible for millions of infections and hundreds of thousands of deaths. The current method for managing influenza is vaccination using a standardized amount of the influenza...
2.
Praznik A, Fink T, Franko N, Lonzaric J, Bencina M, Jerala N, et al.
Nat Commun
. 2022 Mar;
13(1):1323.
PMID: 35260576
Secreted proteins, such as hormones or cytokines, are key mediators in multicellular organisms. Response of protein secretion based on transcriptional control is rather slow, as it requires transcription, translation and...
3.
Fink T, Lonzaric J, Praznik A, Plaper T, Merljak E, Leben K, et al.
Nat Chem Biol
. 2018 Dec;
15(2):115-122.
PMID: 30531965
Cellular signal transduction is predominantly based on protein interactions and their post-translational modifications, which enable a fast response to input signals. Owing to difficulties in designing new unique protein-protein interactions,...
4.
Lonzaric J, Lebar T, Majerle A, Mancek-Keber M, Jerala R
Nucleic Acids Res
. 2016 Jan;
44(3):1471-81.
PMID: 26748097
Development of orthogonal, designable and adjustable transcriptional regulators is an important goal of synthetic biology. Their activity has been typically modulated through stimulus-induced oligomerization or interaction between the DNA-binding and...
5.
Lebar T, Bezeljak U, Golob A, Jerala M, Kadunc L, Pirs B, et al.
Nat Commun
. 2014 Sep;
5:5007.
PMID: 25264186
Bistable switches are fundamental regulatory elements of complex systems, ranging from electronics to living cells. Designed genetic toggle switches have been constructed from pairs of natural transcriptional repressors wired to...