Jan Laco
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Explore the profile of Jan Laco including associated specialties, affiliations and a list of published articles.
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152
Citations
2470
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Recent Articles
11.
Laco J, Vosmikova H, Satankova J, Dedkova J, Mejzlik J, Chrobok V, et al.
Virchows Arch
. 2024 Nov;
PMID: 39565412
This report documents the first case of a conventional (bone-type) giant cell tumor of the larynx, in which the diagnosis was confirmed by molecular genetic analysis. A 50-year-old non-smoking man...
12.
Bradova M, Costes-Martineau V, Laco J, Vanecek T, Grossmann P, Nemcova J, et al.
Histopathology
. 2024 Nov;
86(4):585-602.
PMID: 39564605
Aims: Sinonasal adenosquamous carcinoma (ASC) is a rare tumour classified as a variant of squamous cell carcinoma, exhibiting both squamous and glandular differentiation. ASC has a poorer prognosis compared to...
13.
Othman B, Bradova M, Simpson R, Laco J, Agaimy A, Rito M, et al.
Virchows Arch
. 2024 Nov;
PMID: 39537991
Sclerosing mucoepidermoid carcinoma (SMEC) of the salivary glands is a rare variant of low-grade mucoepidermoid carcinoma with scanty cellular atypia characterized by marked fibrosis/sclerosis and a rich inflammatory infiltrate. Herein,...
14.
Agaimy A, Antonescu C, Bell D, Breimer G, Dermawan J, Kester L, et al.
Virchows Arch
. 2024 Oct;
PMID: 39387893
The FGFR3::TACC3 fusion has been reported in subsets of diverse cancers including urothelial and squamous cell carcinomas (SCC). However, the morphology of FGFR3::TACC3-positive head and neck carcinomas has not been...
15.
Flidrova M, Hajkova N, Hojny J, Dvorak J, Michalkova R, Krkavcova E, et al.
Mod Pathol
. 2024 Sep;
37(12):100611.
PMID: 39265954
Uterine tumor resembling ovarian sex cord tumor (UTROSCT) is a rare tumor of uncertain lineage and low malignant potential. Most tumors behave in a benign manner, but a subset of...
16.
Dvorak O, Slavickova M, Laco J, Stepan M, cermakova E, Spacek J
Ceska Gynekol
. 2024 Sep;
89(4):261-268.
PMID: 39242200
Objective: To investigate DNA methylation of specific tumor suppressor genes in endometrial hyperplasia compared to normal endometrial tissue. File and methodology: To search for epigenetic events, methylation-specific multiplex ligation-dependent probe...
17.
Nemejcova K, Safanda A, Kendall Bartu M, Hajkova N, Drozenova J, Fabian P, et al.
Int J Gynecol Pathol
. 2024 Sep;
PMID: 39230502
Using immunohistochemistry, we examined a large cohort of 135 ovarian tumors, made up of 96 low-grade serous carcinomas (LGSCs) and 39 serous borderline tumors (micropapillary variant, mSBT), with the aim...
18.
Safanda A, Kendall Bartu M, Michalkova R, Svajdler M, Shatokhina T, Laco J, et al.
Diagn Pathol
. 2024 Aug;
19(1):118.
PMID: 39215355
Background: Stathmin, a cytosolic microtubule-destabilizing phosphoprotein involved in the regulation of mitosis, is widely expressed in various malignancies and acts as an adverse prognostic factor. Our research analyzed its immunohistochemical...
19.
Lanickova T, Hensler M, Kasikova L, Vosahlikova S, Angelidou A, Pasulka J, et al.
Clin Cancer Res
. 2024 Aug;
31(1):164-180.
PMID: 39163092
Purpose: Patients with high-grade serous ovarian carcinoma (HGSOC) are virtually insensitive to immune checkpoint inhibitors (ICI) employed as standalone therapeutics, at least in part reflecting microenvironmental immunosuppression. Thus, conventional chemotherapeutics...
20.
Svejdova A, Homolac M, Krtickova J, Laco J, Mejzlik J, Dedkova J, et al.
Laryngoscope
. 2024 Jun;
134(12):5131-5134.
PMID: 38922938
Pseudogout is characterized by the deposition of calcium pyrophosphate dihydrate crystals (CPPD), primarily affecting large joints. Extra-articular manifestations, particularly in the head and neck region, are exceedingly rare. We report...