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Jan Kristoff

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Articles 19
Citations 621
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Recent Articles
11.
Wijewardana V, Kristoff J, Xu C, Ma D, Haret-Richter G, Stock J, et al.
PLoS Pathog . 2013 Oct; 9(10):e1003600. PMID: 24098110
We assessed the role of myeloid dendritic cells (mDCs) in the outcome of SIV infection by comparing and contrasting their frequency, mobilization, phenotype, cytokine production and apoptosis in pathogenic (pigtailed...
12.
Ma D, Jasinska A, Kristoff J, Grobler J, Turner T, Jung Y, et al.
PLoS Pathog . 2013 Jan; 9(1):e1003011. PMID: 23349627
Pathogenesis studies of SIV infection have not been performed to date in wild monkeys due to difficulty in collecting and storing samples on site and the lack of analytical reagents...
13.
Pandrea I, Cornell E, Wilson C, Ribeiro R, Ma D, Kristoff J, et al.
Blood . 2012 Jun; 120(7):1357-66. PMID: 22653975
HIV infection is associated with increased risk of cardiovascular complications, the underlying mechanism of which remains unclear. Plasma levels of the coagulation biomarker D-dimer (DD) correlate with increased mortality and...
14.
Pandrea I, Parrish N, Raehtz K, Gaufin T, Barbian H, Ma D, et al.
J Virol . 2012 Feb; 86(8):4158-68. PMID: 22318138
African green monkeys (AGMs) are naturally infected with a simian immunodeficiency virus (SIVagm) that is nonpathogenic in its host. Although SIVagm is common and widespread, little is known about the...
15.
Pandrea I, Gaufin T, Gautam R, Kristoff J, Mandell D, Montefiori D, et al.
PLoS Pathog . 2011 Aug; 7(8):e1002170. PMID: 21829366
Understanding the mechanism of infection control in elite controllers (EC) may shed light on the correlates of control of disease progression in HIV infection. However, limitations have prevented a clear...
16.
George M, Brower A, Kling H, Shipley T, Kristoff J, Reinhart T, et al.
AIDS Res Hum Retroviruses . 2010 Oct; 27(2):103-11. PMID: 20961277
The lack of animal models of HIV-related pulmonary arterial hypertension (HIV-PAH) severely limits investigation of this serious disease. While histological evidence of HIV-PAH has been demonstrated in macaques infected with...
17.
Kling H, Shipley T, Patil S, Kristoff J, Bryan M, Montelaro R, et al.
Infect Immun . 2010 Jul; 78(10):4320-30. PMID: 20660609
Pulmonary colonization by the opportunistic pathogen Pneumocystis jiroveci is common in HIV(+) subjects and has been associated with development of chronic obstructive pulmonary disease (COPD). Host and environmental factors associated...
18.
Shipley T, Kling H, Morris A, Patil S, Kristoff J, Guyach S, et al.
J Infect Dis . 2010 Jun; 202(2):302-12. PMID: 20533880
Human immunodeficiency virus (HIV)-infected patients are at increased risk for development of pulmonary complications, including chronic obstructive pulmonary disease (COPD). Inflammation associated with subclinical infection has been postulated to promote...
19.
Ongecha J, Remo A, Kristoff J, Hittner J, Were T, Ouma C, et al.
Clin Immunol . 2007 Oct; 126(2):211-21. PMID: 17945537
Severe malarial anemia (SMA) is a leading cause of mortality among children in sub-Saharan Africa. Although the novel cytokine, interleukin (IL)-23, promotes anemia in chronic inflammatory diseases, the role of...
20.
Kristoff J
Curr Pharm Des . 2007 Jul; 13(19):1989-99. PMID: 17627532
Malaria causes 300-500 million clinical cases and 1-3 million deaths per year, the majority of which occur in African children less than five years of age. The failure of vector...