Jan Komorowski
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Explore the profile of Jan Komorowski including associated specialties, affiliations and a list of published articles.
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143
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5899
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Recent Articles
11.
Barrenas F, Hansen S, Law L, Driscoll C, Green R, Smith E, et al.
PLoS Pathog
. 2021 Jul;
17(7):e1009278.
PMID: 34228762
Simian immunodeficiency virus (SIV) challenge of rhesus macaques (RMs) vaccinated with strain 68-1 Rhesus Cytomegalovirus (RhCMV) vectors expressing SIV proteins (RhCMV/SIV) results in a binary outcome: stringent control and subsequent...
12.
Stepniak K, Machnicka M, Mieczkowski J, Macioszek A, Wojtas B, Gielniewski B, et al.
Nat Commun
. 2021 Jun;
12(1):3621.
PMID: 34131149
Chromatin structure and accessibility, and combinatorial binding of transcription factors to regulatory elements in genomic DNA control transcription. Genetic variations in genes encoding histones, epigenetics-related enzymes or modifiers affect chromatin...
13.
Pan G, Diamanti K, Cavalli M, Gutierrez A, Komorowski J, Wadelius C
Life Sci Alliance
. 2021 Jun;
4(7).
PMID: 34099540
Recent studies suggested that dysregulated plays a pivotal role in many liver diseases. To obtain a detailed view of genes and pathways regulated by YY1 in the liver, we carried...
14.
Garbulowski M, Smolinska K, Diamanti K, Pan G, Maqbool K, Feuk L, et al.
Front Genet
. 2021 Mar;
12:618277.
PMID: 33719335
Autism spectrum disorder (ASD) is a heterogeneous neuropsychiatric disorder with a complex genetic background. Analysis of altered molecular processes in ASD patients requires linear and nonlinear methods that provide interpretable...
15.
Garbulowski M, Diamanti K, Smolinska K, Baltzer N, Stoll P, Bornelov S, et al.
BMC Bioinformatics
. 2021 Mar;
22(1):110.
PMID: 33676405
Background: Machine learning involves strategies and algorithms that may assist bioinformatics analyses in terms of data mining and knowledge discovery. In several applications, viz. in Life Sciences, it is often...
16.
Stratmann S, Yones S, Mayrhofer M, Norgren N, Skaftason A, Sun J, et al.
Blood Adv
. 2021 Feb;
5(3):900-912.
PMID: 33560403
Relapse is the leading cause of death of adult and pediatric patients with acute myeloid leukemia (AML). Numerous studies have helped to elucidate the complex mutational landscape at diagnosis of...
17.
Kutashev K, Franek M, Diamanti K, Komorowski J, Olsinova M, Dvorackova M
Plant J
. 2020 Dec;
105(6):1534-1548.
PMID: 33314374
Arabidopsis thaliana 45S ribosomal genes (rDNA) are located in tandem arrays called nucleolus organizing regions on the termini of chromosomes 2 and 4 (NOR2 and NOR4) and encode rRNA, a...
18.
Diamanti K, Visvanathar R, Pereira M, Cavalli M, Pan G, Kumar C, et al.
Sci Rep
. 2020 May;
10(1):8343.
PMID: 32433479
Alteration of various metabolites has been linked to type 2 diabetes (T2D) and insulin resistance. However, identifying significant associations between metabolites and tissue-specific phenotypes requires a multi-omics approach. In a...
19.
Cavalli M, Diamanti K, Pan G, Spalinskas R, Kumar C, Deshmukh A, et al.
OMICS
. 2020 Mar;
24(4):180-194.
PMID: 32181701
The liver is the largest solid organ and a primary metabolic hub. In recent years, intact cell nuclei were used to perform single-nuclei RNA-seq (snRNA-seq) for tissues difficult to dissociate...
20.
Rheinbay E, Nielsen M, Abascal F, Wala J, Shapira O, Tiao G, et al.
Nature
. 2020 Feb;
578(7793):102-111.
PMID: 32025015
The discovery of drivers of cancer has traditionally focused on protein-coding genes. Here we present analyses of driver point mutations and structural variants in non-coding regions across 2,658 genomes from...