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Jan Hansmann

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Articles 79
Citations 911
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Recent Articles
1.
Koniger L, Malkmus C, Mahdy D, Daullary T, Gotz S, Schwarz T, et al.
Adv Sci (Weinh) . 2024 Sep; 11(45):e2406608. PMID: 39324843
The Food and Drug Administration's recent decision to eliminate mandatory animal testing for drug approval marks a significant shift to alternative methods. Similarly, the European Parliament is advocating for a...
2.
Rindt W, Krug M, Yamada S, Sennefelder F, Belz L, Cheng W, et al.
Acta Biomater . 2024 Jul; 184:210-225. PMID: 38969078
Osteocytes perceive and process mechanical stimuli in the lacuno-canalicular network in bone. As a result, they secrete signaling molecules that mediate bone formation and resorption. To date, few three-dimensional (3D)...
3.
Schwedhelm I, Zdzieblo D, Appelt-Menzel A, Berger C, Schmitz T, Schuldt B, et al.
Sci Rep . 2024 Apr; 14(1):7773. PMID: 38565610
No abstract available.
4.
Gensler M, Malkmus C, Ockermann P, Mollmann M, Hahn L, Salehi S, et al.
Bioengineering (Basel) . 2024 Jan; 11(1). PMID: 38247945
Bioprinting provides a powerful tool for regenerative medicine, as it allows tissue construction with a patient's specific geometry. However, tissue culture and maturation, commonly supported by dynamic bioreactors, are needed....
5.
Yamada S, Ockermann P, Schwarz T, Mustafa K, Hansmann J
Comput Struct Biotechnol J . 2023 Sep; 21:4395-4407. PMID: 37711188
Bone is a dynamic environment where osteocytes, osteoblasts, and mesenchymal stem/progenitor cells perceive mechanical cues and regulate bone metabolism accordingly. In particular, interstitial fluid flow in bone and bone marrow...
6.
Weigel T, Christ B, Dembski S, Ewald A, Groneberg D, Hansmann J, et al.
Adv Healthc Mater . 2023 Sep; 12(30):e2301131. PMID: 37660290
Bacterial infection is a crucial complication in implant restoration, in particular in permanent skin-penetrating implants. Therein, the resulting gap between transcutaneous implant and skin represents a permanent infection risk, limiting...
7.
Dembski S, Schwarz T, Oppmann M, Bandesha S, Schmid J, Wenderoth S, et al.
Sci Rep . 2023 Jul; 13(1):11440. PMID: 37454142
Robotic systems facilitate relatively simple human-robot interaction for non-robot experts, providing the flexibility to implement different processes. In this context, shorter process times, as well as an increased product and...
8.
Yamada S, Yassin M, Torelli F, Hansmann J, Green J, Schwarz T, et al.
Bioeng Transl Med . 2023 May; 8(3):e10509. PMID: 37206242
The fate determination of bone marrow mesenchymal stem/stromal cells (BMSC) is tightly regulated by mechanical cues, including fluid shear stress. Knowledge of mechanobiology in 2D culture has allowed researchers in...
9.
Fey P, Weber D, Stebani J, Morchel P, Jakob P, Hansmann J, et al.
PLoS Comput Biol . 2023 Feb; 19(2):e1010842. PMID: 36802391
In order to treat degenerative diseases, the importance of advanced therapy medicinal products has increased in recent years. The newly developed treatment strategies require a rethinking of the appropriate analytical...
10.
Egger D, Hansmann J, Kasper C, Kouroupis D
Front Bioeng Biotechnol . 2022 Sep; 10:999765. PMID: 36110321
No abstract available.