Jan De Mey
Overview
Explore the profile of Jan De Mey including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
755
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0
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Recent Articles
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Mousson A, Legrand M, Steffan T, Vauchelles R, Carl P, Gies J, et al.
Cancers (Basel)
. 2021 Apr;
13(8).
PMID: 33919725
The nonreceptor tyrosine kinase FAK is a promising target for solid tumor treatment because it promotes invasion, tumor progression, and drug resistance when overexpressed. Investigating the role of FAK in...
4.
Fructuoso M, Legrand M, Mousson A, Steffan T, Vauchelles R, De Mey J, et al.
Biol Cell
. 2019 Dec;
112(2):53-72.
PMID: 31859373
Background: Fibroblasts executing directional migration position their centrosome, and their Golgi apparatus, in front of the nucleus towards the cell leading edge. Centrosome positioning relative to the nucleus has been...
5.
Mousson A, Sick E, Carl P, Dujardin D, De Mey J, Ronde P
Cancers (Basel)
. 2018 Aug;
10(9).
PMID: 30134553
Focal adhesion kinase (FAK) is a cytoplasmic non-receptor protein tyrosine kinase that is overexpressed and activated in many human cancers. FAK transmits signals to a wide range of targets through...
6.
Michel G, Matthes H, Hachet-Haas M, El Baghdadi K, De Mey J, Pepperkok R, et al.
J Cell Sci
. 2013 Dec;
127(Pt 4):773-87.
PMID: 24338366
The mTORC1 kinase promotes cell growth in response to growth factors by activation of receptor tyrosine kinase. It is regulated by the cellular energy level and the availability of nutrients....
7.
Brants J, Semenchenko K, Wasylyk C, Robert A, Carles A, Zambrano A, et al.
PLoS One
. 2012 Dec;
7(12):e51258.
PMID: 23251473
hTTLL12 is a member of the tubulin tyrosine ligase (TTL) family that is highly conserved in phylogeny. It has both SET-like and TTL-like domains, suggesting that it could have histone...
8.
Merdes A, De Mey J
Methods Mol Biol
. 2011 Jul;
777:209-21.
PMID: 21773931
The movement of chromosomes in mitosis requires spindle microtubules, as well as a set of specific motor proteins located at the kinetochores of the chromosomes. The exact mechanisms of chromosome...
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Deramaudt T, Dujardin D, Hamadi A, Noulet F, Kolli K, De Mey J, et al.
Mol Biol Cell
. 2011 Feb;
22(7):964-75.
PMID: 21289086
Cell migration is a highly complex process that requires the coordinated formation of membrane protrusion and focal adhesions (FAs). Focal adhesion kinase (FAK), a major signaling component of FAs, is...
10.
Fritz J, Dujardin D, Godet J, Didier P, De Mey J, Darlix J, et al.
J Virol
. 2009 Nov;
84(3):1585-96.
PMID: 19923179
During HIV-1 assembly, the viral protein R (Vpr) is incorporated into newly made viral particles via an interaction with the C-terminal domain of the Gag polyprotein precursor Pr55(Gag). Vpr has...