Jan Chyba
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Explore the profile of Jan Chyba including associated specialties, affiliations and a list of published articles.
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6
Citations
17
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Recent Articles
1.
Chyba J, Hruzikova A, Knor M, Pikulova P, Markova K, Novotny J, et al.
Inorg Chem
. 2023 Feb;
62(8):3381-3394.
PMID: 36763803
In recent decades, transition-metal coordination compounds have been extensively studied for their antitumor and antimetastatic activities. In this work, we synthesized a set of symmetric and asymmetric Ru(III) and Rh(III)...
2.
Sojka M, Chyba J, Paul S, Wawrocka K, Honigova K, Cuyacot B, et al.
Inorg Chem
. 2021 Nov;
60(23):17911-17925.
PMID: 34738800
Platinum-based anticancer drugs are actively developed utilizing lipophilic ligands or drug carriers for the efficient penetration of biomembranes, reduction of side effects, and tumor targeting. We report the development of...
3.
Malali S, Chyba J, Knor M, Horni M, Necas M, Novotny J, et al.
Inorg Chem
. 2020 Jul;
59(14):10185-10196.
PMID: 32633504
A wide range of ruthenium-based coordination compounds have been reported to possess potential as metallodrugs with anticancer or antimetastatic activity. In this work, we synthesized a set of new zwitterionic...
4.
Chyba J, Novak M, Munzarova P, Novotny J, Marek R
Inorg Chem
. 2018 Apr;
57(15):8735-8747.
PMID: 29620874
The potential of paramagnetic ruthenium(III) compounds for use as anticancer metallodrugs has been investigated extensively during the past several decades. However, the means by which these ruthenium compounds are transported...
5.
Chyba J, Moravec Z, Necas M, Mathur S, Pinkas J
Inorg Chem
. 2014 Mar;
53(7):3753-62.
PMID: 24617956
New molecular aluminophosphates of different nuclearity are synthesized by a stepwise process and structurally characterized. The alkane elimination reaction of bis(trimethylsiloxy)phosphoric acid, OP(OH)(OSiMe3)2, with trialkylalanes, AlR3 (R = Me, Et,...
6.
Chyba J, Necas M, Pinkas J
Acta Crystallogr Sect E Struct Rep Online
. 2014 Jan;
69(Pt 12):o1824.
PMID: 24454249
The title compound, C25H24N3O3P, was obtained by catalytic phospho-nation of 4'-(4-bromphen-yl)-2,2':6',2''-terpyridine. The terpyridine moiety is nearly planar, the dihedral angles between the central and the outer rings being 4.06 (9)...