Jan Choutka
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Explore the profile of Jan Choutka including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
221
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Recent Articles
1.
Choutka J, Kaminsky J, Wang E, Parkan K, Pohl R
J Chem Inf Model
. 2025 Jan;
65(2):762-777.
PMID: 39754572
The use of quantum mechanical potentials in protein-ligand affinity prediction is becoming increasingly feasible with growing computational power. To move forward, validation of such potentials on real-world challenges is necessary....
2.
Bancik K, Konecny J, Konecny J, Mikus M, Choutka J, Hercik R, et al.
Sensors (Basel)
. 2024 Dec;
24(23).
PMID: 39686222
As the need to monitor agriculture parameters intensifies, the development of new sensor nodes for data collection is crucial. These sensor types naturally require power for operation, but conventional battery-based...
3.
Choutka J, Parkan K, Pohl R, Kaminsky J
Carbohydr Res
. 2024 Jan;
535:109021.
PMID: 38171193
Aryl C-glycosides, in which the glycosidic bond is changed to a carbon-carbon bond, are an important family of biologically-active compounds. They often serve as secondary metabolites or exhibit antibiotic and...
4.
Choutka J, Kratochvil M, Cisarova I, Pohl R, Kaminsky J, Parkan K
Org Biomol Chem
. 2022 Jul;
20(38):7613-7621.
PMID: 35861668
Modification of the carbohydrate scaffold is an important theme in drug and vaccine discovery. Therefore, the preparation of novel types of glycomimetics is of interest in synthetic carbohydrate chemistry. In...
5.
Choutka J, Jansari V, Hornig M, Iwasaki A
Nat Med
. 2022 Jul;
28(8):1723.
PMID: 35859204
No abstract available.
6.
Choutka J, Jansari V, Hornig M, Iwasaki A
Nat Med
. 2022 May;
28(5):911-923.
PMID: 35585196
SARS-CoV-2 is not unique in its ability to cause post-acute sequelae; certain acute infections have long been associated with an unexplained chronic disability in a minority of patients. These post-acute...
7.
Vankova K, Rahm M, Choutka J, Pohl R, Parkan K
Chemistry
. 2021 Jun;
27(41):10488.
PMID: 34180093
Invited for the cover of this issue is Kamil Parkan and co-workers at University of Chemistry and Technology and Institute of Organic Chemistry and Biochemistry, Prague. The cover graphic depicts...
8.
Vankova K, Rahm M, Choutka J, Pohl R, Parkan K
Chemistry
. 2021 May;
27(41):10583-10588.
PMID: 34048112
Access to unprotected (hetero)aryl pseudo-C-glucosides via a mild Pd-catalysed Hiyama cross-coupling reaction of protecting-group-free 1-diisopropylsilyl-d-glucal with various (hetero)aryl halides has been developed. In addition, selected unprotected pseudo-C-glucosides were stereoselectively converted...
9.
Choutka J, Kratochvil M, Zyka J, Pohl R, Parkan K
Carbohydr Res
. 2020 Aug;
496:108086.
PMID: 32828008
A straightforward and scalable method for the synthesis of protected 2-hydroxyglycals is described. The approach is based on the chlorination of carbohydrate-derived hemiacetals, followed by an elimination reaction to establish...
10.
Choutka J, Pohl R, Parkan K
ACS Omega
. 2019 Aug;
3(7):7875-7887.
PMID: 31458930
The development of effective protection strategies is essential in the synthesis of complex carbohydrates and glycomimetics. This article describes a versatile four-stage protocol for the synthesis of α- or β-aryl--glycosides...