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Jan-Philip Prahl

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Citations 122
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Recent Articles
1.
Liu D, Hwang H, Otoupal P, Geiselman G, Kim J, Pomraning K, et al.
Metab Eng . 2023 May; 78:72-83. PMID: 37201565
Microbial production of valuable bioproducts is a promising route towards green and sustainable manufacturing. The oleaginous yeast, Rhodosporidium toruloides, has emerged as an attractive host for the production of biofuels...
2.
Eng T, Banerjee D, Lau A, Bowden E, Herbert R, Trinh J, et al.
Metab Eng . 2021 May; 66:229-238. PMID: 33964456
Pseudomonas putida KT2440 is an emerging biomanufacturing host amenable for use with renewable carbon streams including aromatics such as para-coumarate. We used a pooled transposon library disrupting nearly all (4,778)...
3.
Kirby J, Geiselman G, Yaegashi J, Kim J, Zhuang X, Tran-Gyamfi M, et al.
Biotechnol Biofuels . 2021 Apr; 14(1):101. PMID: 33883010
Background: Mitigation of climate change requires that new routes for the production of fuels and chemicals be as oil-independent as possible. The microbial conversion of lignocellulosic feedstocks into terpene-based biofuels...
4.
Banerjee D, Eng T, Lau A, Sasaki Y, Wang B, Chen Y, et al.
Nat Commun . 2020 Oct; 11(1):5385. PMID: 33097726
High titer, rate, yield (TRY), and scalability are challenging metrics to achieve due to trade-offs between carbon use for growth and production. To achieve these metrics, we take the minimal...
5.
Wehrs M, Thompson M, Banerjee D, Prahl J, Morella N, Barcelos C, et al.
Microb Cell Fact . 2020 Aug; 19(1):167. PMID: 32811554
Background: Despite the latest advancements in metabolic engineering for genome editing and characterization of host performance, the successful development of robust cell factories used for industrial bioprocesses and accurate prediction...
6.
Geiselman G, Zhuang X, Kirby J, Tran-Gyamfi M, Prahl J, Sundstrom E, et al.
Microb Cell Fact . 2020 Feb; 19(1):24. PMID: 32024522
Background: Rhodosporidium toruloides has emerged as a promising host for the production of bioproducts from lignocellulose, in part due to its ability to grow on lignocellulosic feedstocks, tolerate growth inhibitors,...
7.
Liu D, Geiselman G, Coradetti S, Cheng Y, Kirby J, Prahl J, et al.
Biotechnol Bioeng . 2020 Jan; 117(5):1418-1425. PMID: 31981215
Fatty alcohols (FOHs) are important feedstocks in the chemical industry to produce detergents, cosmetics, and lubricants. Microbial production of FOHs has become an attractive alternative to production in plants and...
8.
Wehrs M, Prahl J, Moon J, Li Y, Tanjore D, Keasling J, et al.
Microb Cell Fact . 2019 Dec; 18(1):218. PMID: 31884968
Following publication of the original article [1], the authors have noted that the standard curve in Additional file 1: Figure S7 is incorrect.
9.
Wehrs M, Prahl J, Moon J, Li Y, Tanjore D, Keasling J, et al.
Microb Cell Fact . 2018 Dec; 17(1):193. PMID: 30545355
Background: Beyond pathway engineering, the metabolic state of the production host is critical in maintaining the efficiency of cellular production. The biotechnologically important yeast Saccharomyces cerevisiae adjusts its energy metabolism...
10.
Schuerg T, Prahl J, Gabriel R, Harth S, Tachea F, Chen C, et al.
Biotechnol Biofuels . 2017 Nov; 10:271. PMID: 29167701
Background: Lignocellulosic biomass is an important resource for renewable production of biofuels and bioproducts. Enzymes that deconstruct this biomass are critical for the viability of biomass-based biofuel production processes. Current...