Jamie L McClellan
Overview
Explore the profile of Jamie L McClellan including associated specialties, affiliations and a list of published articles.
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19
Citations
582
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Recent Articles
1.
Choi R, McConahay A, Jeong H, McClellan J, Hardee J, Carson J, et al.
Biochem Biophys Res Commun
. 2017 Oct;
493(3):1236-1242.
PMID: 28962861
Skeletal muscle atrophy is associated with a disruption in protein turnover involving increased protein degradation and suppressed protein synthesis. Although it has been well studied that the IGF-1/PI3K/Akt pathway plays...
2.
Enos R, Velazquez K, Carson M, McClellan J, Nagarkatti P, Nagarkatti M, et al.
PLoS One
. 2016 Dec;
11(12):e0167979.
PMID: 27959936
The purpose of this study was to examine the effect of a 40% high-fat diet (HFD) supplemented with a dietary attainable level of quercetin (0.02%) on body composition, adipose tissue...
3.
Enos R, Velazquez K, McClellan J, Cranford T, Nagarkatti M, Nagarkatti P, et al.
Am J Physiol Gastrointest Liver Physiol
. 2016 Apr;
310(11):G906-19.
PMID: 27033117
High-fat-diet (HFD) consumption is associated with colon cancer risk. However, little is known about how the lipid composition of a HFD can influence prooncogenic processes. We examined the effects of...
4.
Jeong H, Choi R, McClellan J, Piroli G, Frizzell N, Tseng Y, et al.
Biochem Biophys Res Commun
. 2016 Jan;
470(4):783-91.
PMID: 26801556
Recent studies have demonstrated that adult humans have substantial amounts of functioning brown adipose tissue (BAT). Since BAT has been implicated as an anti-obese and anti-diabetic tissue, it is important...
5.
Velazquez K, Enos R, McClellan J, Cranford T, Chatzistamou I, Singh U, et al.
Am J Physiol Gastrointest Liver Physiol
. 2016 Jan;
310(6):G347-58.
PMID: 26744471
Clinical studies have linked microRNA-155 (miR-155) expression in the tumor microenvironment to poor prognosis. However, whether miR-155 upregulation is predictive of a pro- or antitumorigenic response is unclear, as the...
6.
Enos R, Velazquez K, McClellan J, Cranford T, Walla M, Murphy E
Nutr Res
. 2015 May;
35(5):449-59.
PMID: 25934114
It is hypothesized that a high dietary n-6:n-3 (eg, 10-20:1) is partly responsible for the rise in obesity and related health ailments. However, no tightly controlled studies using high-fat diets...
7.
McClellan J, Steiner J, Day S, Enos R, Davis M, Singh U, et al.
Int J Oncol
. 2014 May;
45(2):861-8.
PMID: 24859893
Many observational epidemiologic studies suggest an association between exercise and colon cancer risk. The mechanisms contributing to a preventative effect of exercise on colon cancer are complex and multifaceted. Altered...
8.
Altamemi I, Murphy E, Catroppo J, Zumbrun E, Zhang J, McClellan J, et al.
J Pharmacol Exp Ther
. 2014 May;
350(1):99-109.
PMID: 24817032
The pleiotropic effects of resveratrol include anti-inflammatory, antioxidant, and anticancer activities, and thus unique possibilities exist to explore mechanistic pathways of chemoprevention. The aim of this study was to investigate...
9.
Enos R, Velazquez K, McClellan J, Cranford T, Walla M, Murphy E
PLoS One
. 2014 Apr;
9(4):e94897.
PMID: 24733548
Aims: To examine the effect of manipulating the omega-6:omega-3 (1∶1, 5∶1, 10∶1, and 20∶1) utilizing only α-linolenic and linoleic acid within a clinically-relevant high-fat diet (HFD) composed of up to...
10.
Mahoney S, Davis J, Murphy E, McClellan J, Pena M
Integr Cancer Ther
. 2014 Mar;
13(5):417-24.
PMID: 24626097
Purpose: While fatigue is the most commonly reported symptom of chemotherapy, there are currently no effective treatments for chemotherapy-induced fatigue (CIF). We used a mouse model to examine the benefits...